Increased pulse pressure linked to dementia: further results from the Hypertension in the Very Elderly Trial - HYVET.

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Abstract

High blood pressure (BP) has been associated with increased risk of dementia. Concerns have been raised about lowering BP too far in the very elderly and thereby increasing risk. There is some evidence to suggest a potential 'J'-shaped relationship between DBP and risk of cognitive impairment. This was investigated using data from the HYpertension in the Very Elderly Trial (HYVET).

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Journal

Journal ID (iso-abbrev): J. Hypertens.

Title: Journal of hypertension

ISSN (Electronic): 1473-5598

ISSN (Print): 0263-6352

Publication date (Electronic): Sep 2013

Volume: 31

Issue: 9

Affiliations

[1 ] aImperial College London UK bDepartment of Cardiovascular Diseases, The Studies Coordinating Centre, Division of Hypertension and Cardiovascular Rehabilitation, University of Leuven, Leuven, Belgium cCentre for Epidemiological Studies and Clinical Trials, The Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China dHôpital Broca, Centre de Gerontologie, 54-56 rue Pascal, 75013 Paris France eLondon School of Hygiene and Tropical Medicine, London, UK.

Article

DOI: 10.1097/HJH.0b013e3283622cc6

PubMed ID: 23743809

SO-VID: 455b3642-9806-402e-94c5-4d1dbbe98291

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