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Predictors of Pathologic Complete Response After Neoadjuvant Treatment for Rectal Cancer: A Multicenter Study.
Dawn Armstrong
1 ,
Soundouss Raissouni
2 ,
Julie Price Hiller
3 ,
Jamison Mercer
4 ,
Erin Powell
4 ,
Anthony MacLean
5 ,
Maria Jiang
6 ,
Corinne Doll
2 ,
Rachel Goodwin
7 ,
Eugene Batuyong
2 ,
Kevin Zhou
8 ,
Jose G Monzon
2 ,
Patricia A Tang
2 ,
Daniel Y Heng
2 ,
Winson Y Cheung
8 ,
Michael M Vickers
7
Dec 2015
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Abstract
Pathologic complete response (pCR) to neoadjuvant chemoradiation (CRT) for rectal cancer is associated with better long-term outcomes, and is used as an early indicator of response to novel agents. To assess the rate and predictors of pCR, we performed a retrospective multicenter study involving 5 Canadian cancer centers.