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      The chemical constituents and economic plants of the Euphorbiaceae

      Botanical Journal of the Linnean Society
      Wiley

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          Poisonous Plants of the United States and Canada

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            Antileukemic principles isolated from euphorbiaceae plants.

            Extracts of Euphorbia esula L. and Croton tiglium L., two members of the Euphorbiaceae which have been used widely in folk medicine for treating cancers, showed antileukemic activity against the P-388 lymphocytic leukemia in mice. Systematic fractionation of the extract of Euphorbia esula L. led to characterization of a major antileukemic component as the new diterpenoid diester, ingenol 3,20-dibenzoate. Similar fractionation of Croton oil led to characterization of phorbol 12-tiglate 13-decanoate as an active principle.
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              Chemotaxonomie der Pflanzen

              R Hegnauer (1966)
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                Author and article information

                Journal
                Botanical Journal of the Linnean Society
                Wiley
                00244074
                January 1987
                January 1987
                May 13 2008
                : 94
                : 1-2
                : 293-326
                Article
                10.1111/j.1095-8339.1987.tb01052.x
                4a0fff36-bd8f-4cad-ae48-f510ba299751
                © 2008

                http://doi.wiley.com/10.1002/tdm_license_1

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