Cost-effective floating wind turbines with efficient installations are highly desired in deep waters (> 50 m). This paper presents a submerged floating offshore wind turbines (SFOWT) concept for intermediate water depths (50 – 200 m). The performance of SFOWTs can be improved through a judicious choice of configuration, pretension, and mooring line layout. Four SFOWTs with different configurations and a similar mass, named Cyl-4, Cub-4, Cyl-3, and Hex-3, were designed and analyzed. The responses of the four SFOWTs were predicted under operational condition and extreme condition. The results show that the four SFOWTs exhibited good performance under both conditions. The effect of platform configurations on power output was negligible under the operational condition. Under the extreme condition, among the four SFOWTs, the mean bending moments at the tower base were very close, while the maximum values differed by up to 21.5%, due to the configurations. The effect of wind-wave misalignment under the extreme condition was further analyzed. In general, the motion performances of the four-pontoon SFOWTs, Cyl-4 and Cub-4, were superior to those of the three-pontoon SFOWTs, Cyl-3 and Hex-3. Optimization studies of the mooring system were carried out on Cub-4 with different mooring line pretensions and four mooring layouts. The optimized Cub-4 could reduce the maximum motion responses in the surge, heave, and yaw by 97.7%, 91.5%, and 98.7%, respectively.