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      Integrating Expert Knowledge with Data in Bayesian Networks: Preserving Data-Driven Expectations when the Expert Variables Remain Unobserved

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          Abstract

          When developing a causal probabilistic model, i.e. a Bayesian network (BN), it is common to incorporate expert knowledge of factors that are important for decision analysis but where historical data are unavailable or difficult to obtain. This paper focuses on the problem whereby the distribution of some continuous variable in a BN is known from data, but where we wish to explicitly model the impact of some additional expert variable (for which there is expert judgment but no data). Because the statistical outcomes are already influenced by the causes an expert might identify as variables missing from the dataset, the incentive here is to add the expert factor to the model in such a way that the distribution of the data variable is preserved when the expert factor remains unobserved. We provide a method for eliciting expert judgment that ensures the expected values of a data variable are preserved under all the known conditions. We show that it is generally neither possible, nor realistic, to preserve the variance of the data variable, but we provide a method towards determining the accuracy of expertise in terms of the extent to which the variability of the revised empirical distribution is minimised. We also describe how to incorporate the assessment of extremely rare or previously unobserved events.

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            The EM algorithm for graphical association models with missing data

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              Methods to elicit beliefs for Bayesian priors: a systematic review.

              Bayesian analysis can incorporate clinicians' beliefs about treatment effectiveness into models that estimate treatment effects. Many elicitation methods are available, but it is unclear if any confer advantages based on principles of measurement science. We review belief-elicitation methods for Bayesian analysis and determine if any of them had an incremental value over the others based on its validity, reliability, and responsiveness. A systematic review was performed. MEDLINE, EMBASE, CINAHL, Health and Psychosocial Instruments, Current Index to Statistics, MathSciNet, and Zentralblatt Math were searched using the terms (prior OR prior probability distribution) AND (beliefs OR elicitation) AND (Bayes OR Bayesian). Studies were evaluated on: design, question stem, response options, analysis, consideration of validity, reliability, and responsiveness. We identified 33 studies describing methods for elicitation in a Bayesian context. Elicitation occurred in cross-sectional studies (n=30, 89%), to derive point estimates with individual-level variation (n=19; 58%). Although 64% (n=21) considered validity, 24% (n=8) reliability, 12% (n=4) responsiveness of the elicitation methods, only 12% (n=4) formally tested validity, 6% (n=2) tested reliability, and none tested responsiveness. We have summarized methods of belief elicitation for Bayesian priors. The validity, reliability, and responsiveness of elicitation methods have been infrequently evaluated. Until comparative studies are performed, strategies to reduce the effects of bias on the elicitation should be used. Copyright 2010 Elsevier Inc. All rights reserved.
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                Author and article information

                Journal
                9884333
                36156
                Expert Syst Appl
                Expert Syst Appl
                Expert systems with applications
                0957-4174
                28 June 2016
                18 March 2016
                1 September 2016
                01 September 2016
                : 56
                : 197-208
                Affiliations
                [a ]Risk and Information Management (RIM) Research Group, School of Electronic Engineering and Computer Science, Queen Mary University of London, London, UK, E1 4NS
                [c ]Director of Risk and Information Management (RIM) Research Group, School of Electronic Engineering and Computer Science, Queen Mary University of London, London, UK, E1 4NS. n.fenton@ 123456qmul.ac.uk
                [d ]Director, Agena Ltd, Cambridge, UK, CB23 7NU
                [e ]Risk and Information Management (RIM) Research Group, School of Electronic Engineering and Computer Science, Queen Mary University of London, London, UK, E1 4NS. m.neil@ 123456qmul.ac.uk
                [f ]Director, Agena Ltd, Cambridge, UK, CB23 7NU
                Author notes
                [b ] Corresponding author: Dr. Anthony Constantinou, anthony@ 123456constantinou.info
                Article
                EMS69016
                10.1016/j.eswa.2016.02.050
                4930146
                27378822
                4b7bba01-dcc8-4720-a6ee-0409fa3d2c98

                This manuscript version is made available under the CC-BY-NC-ND 4.0 license: http://creativecommons.org/licenses/by-nc-nd/4.0/

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                Article

                bayesian networks,belief networks,causal inference,expert knowledge,knowledge elicitation,probabilistic graphical models

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