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      The Influence of Surface Wettability and Topography on the Bioactivity of TiO 2/Epoxy Coatings on AISI 316L Stainless Steel

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          Abstract

          Epoxy/TiO 2/epoxy and epoxy/FAS-TiO 2/epoxy coatings were applied to the surface of AISI 316L stainless steel with the aim to improve the biocompatibility and antibacterial properties. Contact-angle measurements were used to evaluate the wetting properties of the epoxy, epoxy/TiO 2/epoxy and epoxy/FAS-TiO 2/epoxy coatings. The epoxy and epoxy/TiO 2/epoxy coatings were hydrophilic compared with the strongly hydrophobic epoxy/FAS-TiO 2/epoxy coating. The average surface roughness ( S a ) of the epoxy/FAS-TiO 2/epoxy coating was higher than that of the epoxy/TiO 2/epoxy coating due to the formation of agglomerates. The biocompatibility evaluation revealed that the cell attachment was significantly higher on the epoxy/FAS-TiO 2/epoxy and epoxy/TiO 2/epoxy coatings compared with the pure epoxy coating. We also observed improved antibacterial properties for the epoxy coatings with the addition of both TiO 2 and FAS-TiO 2 nanoparticles.

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          Direct femtosecond laser surface nano/microstructuring and its applications

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            Contact angle measurement and contact angle interpretation

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              Surface characteristics influencing bacterial adhesion to polymeric substrates

              Effective surface area on rough substrates for bacterial adhesion is examined by analyzing the solid area fraction of surfaces, where the bacterial medium is in contact with the solid surface. Superhydrophobic surfaces have been reported to reduce bacterial adhesion, but interactions between bacterial media and solid surfaces at the interface have rarely been associated with the solid area fraction ( f ) from the Cassie–Baxter wetting state. This study aimed to investigate the effective surface area for bacterial adhesion by analyzing the solid area fraction of surfaces where the bacterial medium is in contact with a solid surface. Also, the self-cleaning ability of the superhydrophobic surface against adhered bacteria was examined. The influences of roughness, surface energy, entrapped air, and surface charge of substrate materials on bacterial adhesion were examined, and the critical surface characteristics that are conducive to reducing Escherichia coli adherence to polymeric surfaces were determined. Moderate hydrophobicity with water contact angle of about 90° produced the highest level of bacterial adhesion. Entrapped air at the interface of superhydrophobic surfaces interfered with the direct contact of bacteria to solid surfaces, leading to less bacterial adhesion. The superhydrophobic surface with a reduced solid area fraction displayed self-cleaning ability, where initially-adhered bacteria were removed by washing. The superhydrophilic substrate with negative zeta potential exhibited limited bacterial binding, due to the reduced hydrophobic interaction and possible repulsive interaction between bacteria and surface. The findings of this study can be utilized for an effective surface design to circumvent bacterial adhesion as an alternative solution to using antibiotics.
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                Author and article information

                Journal
                Materials (Basel)
                Materials (Basel)
                materials
                Materials
                MDPI
                1996-1944
                11 June 2019
                June 2019
                : 12
                : 11
                : 1877
                Affiliations
                Institute of Metals and Technology, Lepi pot 11, SI-1000 Ljubljana, Slovenia; marjetka.conradi@ 123456imt.si (M.C.); matej.hocevar@ 123456imt.si (M.H.)
                Author notes
                [* ]Correspondence: aleksandra.kocijan@ 123456imt.si ; Tel.: +386-1-4701-955
                Article
                materials-12-01877
                10.3390/ma12111877
                6600972
                31212615
                4bde9a26-0a92-4c7b-b254-341b87793195
                © 2019 by the authors.

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).

                History
                : 07 May 2019
                : 10 June 2019
                Categories
                Article

                epoxy coatings,tio2 nanoparticles,biocompatibility,antibacterial properties

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