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      Correction to: Effects of enzymatically modified isoquercitrin in supplementary protein powder on athlete body composition: a randomized, placebo-controlled, doubleblind trial

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          Abstract

          Correction to: J Int Soc Sports Nutr https://doi.org/10.1186/s12970-019-0303-x The original article [1] contained a typesetting error in Table 3 which was mistakenly introduced by the production team handling this article; this error has now been corrected.

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          Effects of enzymatically modified isoquercitrin in supplementary protein powder on athlete body composition: a randomized, placebo-controlled, double-blind trial

          Naomi Omi, Hideki Shiba, Eisaku Nishimura … (2019)
          Background Enzymatically modified isoquercitrin (EMIQ), a water-soluble quercetin, has been shown to intensify muscle hypertrophy in mice. We investigated the effect of EMIQ in supplementary protein powder on athlete body composition. Methods Forty Japanese males who played American football (age: 19.8 ± 1.4 years; body height: 174.1 ± 6.0 cm; body mass: 75.5 ± 10.7 kg) were assigned to a randomized, placebo-controlled, double-blind trial of parallel group. Participants received either EMIQ in whey protein (EW, n = 19) or contrast whey protein (W, n = 20) 6 days per week over 4 months. Body composition was assessed using dual-energy X-ray absorptiometry. Markers of oxidative stress, derivatives of reactive oxygen metabolites (d-ROMs) and biological antioxidant potential (BAP), were assessed using a free radical analytical system. Data were analyzed using a univariate and repeated measures general model statistics. Results After 4 months, changes in lower limb fat-free mass and muscle mass were significantly greater in the EW group than in the W group (mean change ±95% CI; W: 324.1 ± 284.3, EW: 950.3 ± 473.2, p = 0.031, W: 255.7 ± 288.6, EW: 930.9 ± 471.5, p = 0.021, respectively). Moreover, the EW group exhibited a significantly higher BAP/d-ROMs ratio, antioxidation index, than the W group after 4 months (mean change ± SD; W: 8.8 ± 1.1, EW: 10.3 ± 2.8; p = 0.028). No significant differences in body mass, lean body mass, fat mass, or lower limb fat mass were observed between the groups. Conclusion Ingestion of EMIQ in supplementary protein powder for 4 months exerts antioxidant effects and increases muscle mass among American football players. Trial registration University Hospital Medical Information Network Clinical Trial Registry, UMIN000036036. Retrospectively registered in 2019.
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            Author and article information

            Contributors
            Naomi Omi: ominaomi@taiiku.tsukuba.ac.jp
            Journal
            Journal ID (nlm-ta): J Int Soc Sports Nutr
            Journal ID (iso-abbrev): J Int Soc Sports Nutr
            Title: Journal of the International Society of Sports Nutrition
            Publisher: BioMed Central (London )
            ISSN (Electronic): 1550-2783
            Publication date (Electronic): 21 October 2019
            Publication date PMC-release: 21 October 2019
            Publication date Collection: 2019
            Volume: 16
            Electronic Location Identifier: 45
            Affiliations
            [1 ]ISNI 0000 0001 2369 4728, GRID grid.20515.33, Faculty of Health and Sport Sciences, , University of Tsukuba, ; Tsukuba, Japan
            [2 ]ISNI 0000 0001 2369 4728, GRID grid.20515.33, Physical Education Graduate School, , University of Tsukuba, ; Tsukuba, Japan
            [3 ]ISNI 0000 0000 8801 3092, GRID grid.419972.0, Health Science Research Center, , Morinaga & Co., Ltd, ; Tokyo, Japan
            Article
            Publisher ID: 315
            DOI: 10.1186/s12970-019-0315-6
            PMC ID: 6805538
            PubMed ID: 31639004
            SO-VID: 4e3a8628-3b63-4ef1-8b74-3f6323470fbf
            Copyright © © The Author(s). 2019
            License:

            Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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            ScienceOpen disciplines: Sports medicine
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            ScienceOpen disciplines: Sports medicine

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