9
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      ACTUALIZACIÓN EN EL FUNCIONAMIENTO DE LA GLÁNDULA TIROIDES EN CANINOS.PRIMERA PARTE:: FUNCIONAMIENTO NORMAL Translated title: UPDATE OF THE THYROID GLAND FUNCTIONING IN CANINES. PART I:: NORMAL FUNCTIONING

      research-article
      ,
      Biosalud
      Universidad de Caldas
      hormones, thyroid, dogs, hormonas, tiroides, perros

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Objetivo. Actualizar conceptos sobre el funcionamiento normal de la glándula tiroides en caninos. Materiales y métodos. Se analizó la literatura disponible de los últimos 50 años en las bases de datos BBCS-LILACS, Fuente Académica, IB-PsycINFO, IB-SSCI, IB-SciELO, Scopus y Scirus, al igual que artículos históricos, textos y referencias citadas en trabajos públicos. Resultados. Se obtuvo información pertinente relacionada con los objetivos propuestos en la presente revisión, por lo cual puede clasificarse en 3 secciones a saber: síntesis de las hormonas tiroideas, transporte de las hormonas tiroideas, funciones de las hormonas tiroideas. Conclusión. La glándula tiroides juega un papel importante, como productora de hormonas tiroideas, siendo necesarias para la diferenciación celular y crecimiento del organismo. El buen funcionamiento de las vías metabólicas depende de estas hormonas, las que tienen efectos específicos sobre diferentes órganos, manteniendo la homeostasis entre todos los tejidos.

          Translated abstract

          Objective. To update concepts related to normal function of the thyroid gland in canines. Materials and methods. Information from the last 50 years including the BBCS-LILACS data bases, Fuente Académica, IB-PsycINFO, IB-SSCI, IB-SciELO, Scopus and Scirus, databases as well as historical articles, texts and references cited in work published to date were analyzed. Results. Pertinent information related with the objectives proposed in the present review was found and analyzed. It was then divided into three sections as follows: synthesis of thyroid hormones, transport of thyroid hormones and functions of thyroid hormones. Conclusion. The thyroid gland plays an important role producing thyroid hormones which are necessary for cellular differentiation and organic growth. The adequate functioning of metabolic ways depends of these hormones, which have specific effects on different organs maintaining homeostasis between all tissues.

          Related collections

          Most cited references65

          • Record: found
          • Abstract: found
          • Article: not found

          Physiological and molecular basis of thyroid hormone action.

          P M Yen (2001)
          Thyroid hormones (THs) play critical roles in the differentiation, growth, metabolism, and physiological function of virtually all tissues. TH binds to receptors that are ligand-regulatable transcription factors belonging to the nuclear hormone receptor superfamily. Tremendous progress has been made recently in our understanding of the molecular mechanisms that underlie TH action. In this review, we present the major advances in our knowledge of the molecular mechanisms of TH action and their implications for TH action in specific tissues, resistance to thyroid hormone syndrome, and genetically engineered mouse models.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Mechanism of thyroid hormone action.

            Thyroid hormone (triiodothyronine [T3]) regulates gene expression by binding to high-affinity nuclear receptors. Thyroid hormone receptors (TRs) recognize specific response element sequences in the promoters of T3-target genes and activate or repress transcription in response to hormone. In this paper, we review the TR proteins and thyroid hormone response elements (TREs) to which they bind, the mechanisms of action of TRs bound to the TRE in basal and liganded conformations, and the interacting proteins implicated in these complexes. We then briefly consider the cross-talk with other signaling pathways and introduce the idea that T3 may also act rapidly via nongenomic actions located on membranes. We discuss patterns of gene expression and specific actions of the various TR isoforms and consider the novel TR isoform specific ligands.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              The effect of thyroid hormone on skeletal integrity.

              Thyroid disease and osteoporosis are common problems often managed by primary care physicians. Despite many studies, confusion still exists about the effect of thyroid hormone on skeletal health. To review evidence on the effect of thyroid hormone (from hyperthyroidism, exogenous or endogenous suppression of thyroid-stimulating hormone [TSH], and thyroid hormone replacement therapy) on skeletal integrity. A MEDLINE search of papers published between 1966 and 1997. Cross-sectional studies, longitudinal studies, and meta-analyses that had appropriate control groups (patients matched for age, sex, and menopausal status), made comparisons with established databases, or defined thyroid state by TSH level or thyroid hormone dose were reviewed. Data synthesis was not straightforward because of changes in doses and types of thyroid hormone preparations; changes in definitions of thyroid hormone replacement therapy and suppressive therapies; problems with study design; differences in skeletal sites assessed (hip, spine, forearm, or heel) and techniques used to measure bone mineral density; and inclusion of heterogenous and changing thyroid disease states. Overall, hyperthyroidism and use of thyroid hormone to suppress TSH because of thyroid cancer, goiters, or nodules seem to have an adverse effect on bone, especially in postmenopausal women; the largest effect is on cortical bone. Thyroid hormone replacement seems to have a minimal clinical effect on bone. Women with a history of hyperthyroidism or TSH suppression by thyroid hormone should have skeletal status assessed by bone mineral densitometry, preferably at a site containing cortical bone, such as the hip or forearm.
                Bookmark

                Author and article information

                Journal
                biosa
                Biosalud
                Biosalud
                Universidad de Caldas (Manizales, Caldas, Colombia )
                1657-9550
                September 2011
                : 10
                : 1
                : 99-112
                Affiliations
                [02] orgnameUniversidad de Caldas orgdiv1Departamento de Salud Animal
                [01] orgnameUniversidad de Caldas orgdiv1Departamento de Ciencias Básicas de la Salud jose.osorio_o@ 123456ucaldas.edu.co
                Article
                S1657-95502011000100009 S1657-9550(11)01000109
                4ead3657-dd54-47b8-84af-c6568ef894a9

                This work is licensed under a Creative Commons Attribution 4.0 International License.

                History
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 66, Pages: 14
                Product

                SciELO Colombia

                Categories
                Artículos

                hormones,perros,tiroides,hormonas,dogs,thyroid
                hormones, perros, tiroides, hormonas, dogs, thyroid

                Comments

                Comment on this article