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The impact of system matrix dimension on small FOV SPECT reconstruction with truncated projections : Small FOV SPECT reconstruction with truncated projections

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      Most cited references 31

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      A fast cardiac gamma camera with dynamic SPECT capabilities: design, system validation and future potential

      Purpose The goal of this study is to present the Discovery NM 530c (DNM), a cardiac SPECT camera, interfacing multi-pinhole collimators with solid-state modules, aiming at slashing acquisition time without jeopardizing quality. DNM resembles PET since it enables 3-D SPECT without detector motion. We further envision how these novel capabilities may help with current and future challenges of cardiac imaging. Methods DNM sensitivity, spatial resolution (SR) and energy resolution (ER), count rate response, cardiac uniformity and cardiac defect contrast were measured and compared to a dedicated cardiac, dual-head standard SPECT (S-SPECT) camera. Results DNM sensitivity was more than threefold higher while SR was notably better. Significantly, SR was the same for 99mTc and 201Tl. ER was improved on DNM and allowed good separation of 99mTc and 123I spectral peaks. Count rate remained linear on DNM up to 612 kcps, while S-SPECT showed severe dead time limitations. Phantom studies revealed comparable uniformity and defect contrast, notwithstanding significantly shorter acquisition time for the DNM. First patient images, including dynamic SPECT, are also presented. Conclusion DNM is raising the bar for expedition and upgrade of practice. It features high sensitivity as well as improved SR, temporal resolution and ER. It enables reduction of acquisition time and fast protocols. Importantly, it is potentially capable of dynamic 3-D acquisition. The new technology is potentially upgradeable and may become a milestone in the evolution of nuclear cardiology as it assumes its key role in molecular imaging of the heart.
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        Truncated Hilbert transform and image reconstruction from limited tomographic data

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          Advances in technical aspects of myocardial perfusion SPECT imaging.

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            Author and article information

            Journal
            Medical Physics
            Med. Phys.
            Wiley
            00942405
            January 2016
            December 23 2015
            December 23 2015
            : 43
            : 1
            : 213-224
            10.1118/1.4938098
            © 2015

            http://doi.wiley.com/10.1002/tdm_license_1

            http://onlinelibrary.wiley.com/termsAndConditions

            http://doi.wiley.com/10.1002/tdm_license_1.1

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