Indications and results of diagnostic biopsy in pediatric renal tumors: A retrospective analysis of 317 patients with critical review of SIOP guidelines.

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Abstract

According to the Renal Tumor Study Group (RTSG) of the International Society of Paediatric Oncology (SIOP), diagnostic biopsy of renal tumors prior to neoadjuvant chemotherapy is not mandatory unless the presentation is atypical for a Wilms tumor (WT). This study addresses the relevance of this strategy as well as the accuracy and safety of image-guided needle biopsy.

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Author and article information

Journal

Journal ID (iso-abbrev): Pediatr Blood Cancer

Title: Pediatric blood & cancer

Publisher: Wiley

ISSN (Electronic): 1545-5017

ISSN (Print): 1545-5009

Publication date (Electronic): June 2019

Volume: 66

Issue: 6

Affiliations

[1 ] Department of Pediatrics, APHP, University Hospital Ambroise Paré, Boulogne-Billancourt, Paris, France.

[2 ] Oncology Center SIREDO (Care, Innovation, Research for Cancer in Children, Adolescents and Young Adults), Institut Curie, Paris, France.

[3 ] University Paris Descartes, Paris, France.

[4 ] Department of Surgery, APHP, University Hospital Necker-Enfants-Malades, Paris, France.

[5 ] Department of Surgery, APHP, University Hospital Robert Debré, Paris, France.

[6 ] Department of Surgery, APHP, University Hospital Armand-Trousseau, Paris, France.

[7 ] Department of Pathology, APHP, University Hospital Armand-Trousseau, Paris, France.

[8 ] Department of Biopathology, Institut Curie, Paris, France.

[9 ] Department of Pathology, APHP, University Hospital Robert Debré, Paris, France.

[10 ] University Paris Diderot, Paris, France.

[11 ] INSERM U830 Transfer Department, RTOP (Translational Research in Pediatric Oncology), Institut Curie, Paris, France.

[12 ] Imaging Department, Institut Curie, Paris, France.

[13 ] Paris Sciences et Lettres Research University, Paris, France.

Article

DOI: 10.1002/pbc.27641

PubMed ID: 30746839

SO-VID: 4f161156-bad9-4c93-bac2-71dff2f1743a

History

Keywords: nephroblastoma,renal tumor,Wilms tumor,children,biopsy

Data availability:

Keywords: nephroblastoma, renal tumor, Wilms tumor, children, biopsy

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