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      Glue-assisted retinopexy for rhegmatogenous retinal detachments (GuARD): A novel surgical technique for closing retinal breaks

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          Abstract

          Purpose:

          This study describes a novel surgical technique of fibrin glue-assisted retinopexy for rhegmatogenous retinal detachment (GuARD) without oil or gas tamponade after pars plana vitrectomy (PPV).

          Methods:

          This pilot clinical trial included five eyes of five patients with rhegmatogenous retinal detachments (RD). A complete PPV was done in all cases followed by fluid–air exchange, laser photocoagulation around the break/s, and application of 0.1–0.2 mL of fibrin glue. No air, long-acting gas or silicone oil was used subsequently. No specific postoperative positioning was prescribed. The primary outcome measure was efficacy of the procedure defined as successful anatomical retinal reattachment. Secondary outcome measures were postoperative improvement in best corrected visual acuity (BCVA) and complications.

          Results:

          The median age of patients was 55 (range: 36–61 years) years and median duration of symptoms was 15 (range: 7–60) days. All eyes were pseudophakic, four eyes had inferior and one eye had total RD. Successful retinal reattachment was achieved in all (100%) cases and was maintained at the end of 3–8 months of follow-up. The median BCVA improved from 20/100 preoperatively to 20/80 at 1-week and 20/50 at 1-month postoperatively. None of the eyes had any postoperative complications such as elevated intraocular pressures or unexpected inflammation.

          Conclusion:

          The findings of this study suggest that GuARD is a promising technique for treatment of rhegmatogenous RD that may allow early visual recovery while avoiding the problems of gas or oil tamponade and obviating the need of postoperative positioning.

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          Most cited references18

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          Complications associated with the use of silicone oil in 150 eyes after retina-vitreous surgery.

          Complicated retinal detachments (RDs) were successfully managed in 150 eyes of 170 consecutive patients by one surgeon (JLF) using silicone oil in conjunction with modern pars plana vitrectomy. Long-term postoperative complications were observed between 6 months and 5 years of follow-up. Cataracts developed in all phakic eyes and all corneas with oil-endothelial touch showed band keratopathy within 6 months. Recurrent detachments were noted in 22% of eyes during silicone oil tamponade and occurred in 13% of eyes after the oil had been removed. Other complications associated with the use of oil for vitreous surgery included pupillary block glaucoma (3%), closure of the inferior iridectomy (14%), fibrous epiretinal and subretinal proliferations (15%), pain (5%), and subconjunctival deposits of oil (3%). Without exception, within a period of 1 year the intraocular silicone oil showed some degree of emulsification, suggesting that the physicochemical characteristics of the oil injected may be an important variable in long-term complications.
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            Is Open Access

            Simple Limbal Epithelial Transplantation: Long-Term Clinical Outcomes in 125 Cases of Unilateral Chronic Ocular Surface Burns.

            This study describes the long-term clinical outcomes of autologous simple limbal epithelial transplantation (SLET), a relatively new technique of limbal stem cell transplantation.
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              • Article: not found

              Strategy for the management of uncomplicated retinal detachments: the European vitreo-retinal society retinal detachment study report 1.

              To study success and failure in the treatment of uncomplicated rhegmatogenous retinal detachments (RRDs).
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                Author and article information

                Journal
                Indian J Ophthalmol
                Indian J Ophthalmol
                IJO
                Indian Journal of Ophthalmology
                Medknow Publications & Media Pvt Ltd (India )
                0301-4738
                1998-3689
                May 2019
                : 67
                : 5
                : 677-680
                Affiliations
                [1]Smt. Kanuri Santhamma Center for Vitreo Retina Services, Hyderabad, Telangana, India
                [1 ]Center for Ocular Regeneration, L V Prasad Eye Institute, Hyderabad, Telangana, India
                Author notes
                Correspondence to: Dr. Sayan Basu, Center for Ocular Regeneration (CORE), Kallam Anji Reddy Campus, L V Prasad Eye Institute, Hyderabad - 500 034, Telangana, India. E-mail: sayanbasu@ 123456lvpei.org
                Article
                IJO-67-677
                10.4103/ijo.IJO_1943_18
                6498943
                31007238
                4f6a3656-1348-4f45-acb1-fa40805308f6
                Copyright: © 2019 Indian Journal of Ophthalmology

                This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.

                History
                : 22 November 2018
                : 03 January 2019
                Categories
                Surgical Technique

                Ophthalmology & Optometry
                fibrin glue,retinal detachment surgery,rhegmatogenous retinal detachment

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