For Publishers
DiscoveryMetadataPeer reviewHostingPublishing
For Researchers
JoinPublishReviewCollect
Register
Blog
About
Search
Advanced search
My ScienceOpen
Search
For Publishers
For Researchers
Blog
About
11
views
72
references
 Top references
cited by
12
    
0 reviews
 Review
0
comments
 Comment
0
recommends
+1 Recommend
0 collections
    0
    shares
      75
      similar
       All similar
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Some aspects of radical chemistry in the assembly of complex molecular architectures

      review-article

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Summary

          This review article describes briefly some of the radical processes developed in the authors’ laboratory as they pertain to the concise assembly of complex molecular scaffolds. The emphasis is placed on the use of nitrogen-centred radicals, on the degenerate addition–transfer of xanthates, especially on its potential for intermolecular carbon–carbon bond formation, and on the generation and capture of radicals through electron transfer processes.

          Abstract

          Related collections

          Most cited references72

          • Record: found
          • Abstract: found
          • Article: not found

          Recent progress in the generation and use of nitrogen-centred radicals.

          Samir Zard (2008)
          Nitrogen-centred radicals hold much promise as useful synthetic intermediates. Even though their popularity is still extremely limited and very far from matching that of carbon radicals, the recent development of various routes allowing their generation under mild conditions and a better appreciation of their reactivity thanks to the increased availability of absolute rate constants should encourage their use. It is hoped that this tutorial review will help increase the awareness of synthetic chemists and help revive the interest in these forgotten species.
          Article 0 comments Cited 183 times – based on 0 reviews     Review now
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            A general model for selectivity in olefin cross metathesis.

            Arnab Chatterjee, Tae-Lim Choi, Daniel Sanders … (2003)
            In recent years, olefin cross metathesis (CM) has emerged as a powerful and convenient synthetic technique in organic chemistry; however, as a general synthetic method, CM has been limited by the lack of predictability in product selectivity and stereoselectivity. Investigations into olefin cross metathesis with several classes of olefins, including substituted and functionalized styrenes, secondary allylic alcohols, tertiary allylic alcohols, and olefins with alpha-quaternary centers, have led to a general model useful for the prediction of product selectivity and stereoselectivity in cross metathesis. As a general ranking of olefin reactivity in CM, olefins can be categorized by their relative abilities to undergo homodimerization via cross metathesis and the susceptibility of their homodimers toward secondary metathesis reactions. When an olefin of high reactivity is reacted with an olefin of lower reactivity (sterically bulky, electron-deficient, etc.), selective cross metathesis can be achieved using feedstock stoichiometries as low as 1:1. By employing a metathesis catalyst with the appropriate activity, selective cross metathesis reactions can be achieved with a wide variety of electron-rich, electron-deficient, and sterically bulky olefins. Application of this model has allowed for the prediction and development of selective cross metathesis reactions, culminating in unprecedented three-component intermolecular cross metathesis reactions.
            Article 0 comments Cited 180 times – based on 0 reviews     Review now
              Bookmark
              • Record: found
              • Abstract: not found
              • Article: not found

              Claisen rearrangement over the past nine decades.

              Ana Martín Castro (2004)
              Article 0 comments Cited 122 times – based on 0 reviews     Review now
                Bookmark
                All references

                Author and article information

                Contributors
                Samir Z Zard
                Donald Craig: Role: Guest Editor
                Journal
                Journal ID (nlm-ta): Beilstein J Org Chem
                Journal ID (iso-abbrev): Beilstein J Org Chem
                Title: Beilstein Journal of Organic Chemistry
                Publisher: Beilstein-Institut (Trakehner Str. 7-9, 60487 Frankfurt am Main, Germany )
                ISSN (Electronic): 1860-5397
                Publication date Collection: 2013
                Publication date (Electronic): 18 March 2013
                Volume: 9
                Pages: 557-576
                Affiliations
                [1 ]Laboratoire de Synthèse Organique, CNRS UMR 7652, Ecole Polytechnique, 91128 Palaiseau, France
                Article
                DOI: 10.3762/bjoc.9.61
                PMC ID: 3629037
                PubMed ID: 23616797
                SO-VID: 4f71a1cd-b85f-4302-88ae-9fc9b9aad01b
                Copyright © Copyright © 2013, Quiclet-Sire and Zard; licensee Beilstein-Institut.
                License:

                This is an Open Access article under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: ( http://www.beilstein-journals.org/bjoc)

                History
                Date received : 2 January 2013
                Date accepted : 25 February 2013
                Categories
                Subject: Review
                Subject: Chemistry
                Subject: Organic Chemistry

                ScienceOpen disciplines: Organic & Biomolecular chemistry
                Keywords: amidyls,iminyls,radical allylation,radical vinylation,xanthate transfer
                Data availability:
                ScienceOpen disciplines: Organic & Biomolecular chemistry
                Keywords: amidyls, iminyls, radical allylation, radical vinylation, xanthate transfer

                Comments

                Comment on this article

                scite_

                Similar content75

                See all similar

                Cited by11

                See all cited by

                Most referenced authors389

                See all reference authors