- Record: found
- Abstract: found
- Article: not found
Physical activity, tumor PTGS2 expression, and survival in patients with colorectal cancer.
Mai Yamauchi
1 ,
Paul Lochhead ,
Yu Imamura ,
Aya Kuchiba ,
Xiaoyun Liao ,
Zhi Rong Qian ,
Reiko Nishihara ,
Teppei Morikawa ,
Kaori Shima ,
Kana Wu ,
Edward Giovannucci ,
Jeffrey A Meyerhardt ,
Charles S Fuchs ,
Andrew T Chan ,
Shuji Ogino
Jun 2013
Read this article at
There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.
Abstract
Higher levels of physical activity are associated with lower colorectal carcinoma incidence and mortality, perhaps through influencing energy balance, cellular prosta7 systemic inflammation. Although evidence suggests interactive effects of energetics, sedentary lifestyle, and tumor CTNNB1 (β-catenin) or CDKN1B (p27) status on colon cancer prognosis, interactive effects of physical activity and tumor PTGS2 (the official symbol for COX-2) status on clinical outcome remain unknown.