Protein Tyrosine Phosphatase 4A3 (PTP4A3) Promotes Human Uveal Melanoma Aggressiveness Through Membrane Accumulation of Matrix Metalloproteinase 14 (MMP14).

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Abstract

To study PTP4A3 phosphatase and MMP14 metalloprotease synergy in uveal melanoma aggressiveness.

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Journal

Journal ID (iso-abbrev): Invest. Ophthalmol. Vis. Sci.

Title: Investigative ophthalmology & visual science

Publisher: Association for Research in Vision and Ophthalmology (ARVO)

ISSN (Electronic): 1552-5783

ISSN (Print): 0146-0404

Publication date (Electronic): Apr 01 2016

Volume: 57

Issue: 4

Affiliations

[1 ] Institut Curie, PSL Research University, Centre National de La Recherche Scientifique (CNRS), Institut National de la Santé Et de la Recherche Médicale (INSERM), Unité Mixte de Recherche 3347 (UMR), Unité 1021 Orsay, France 2Université Paris Sud, Universi.

[2 ] Residual Tumor & Response to Treatment Lab, Institut Curie - Translational Research Department, Paris, France.

[3 ] Tumor Biology Department, Institut Curie, Paris, France.

[4 ] Department of Medical Oncology, Institut Curie, Paris, France.

[5 ] Department of Surgical Oncology, Institut Curie, Paris, France.

[6 ] Institut Curie, PSL Research University, Centre National de La Recherche Scientifique (CNRS), Institut National de la Santé Et de la Recherche Médicale (INSERM), Unité Mixte de Recherche 3347 (UMR), Unité 1021 Orsay, France 7Université Paris Diderot, Sorb.

Article

Publisher Item ID: 2516675

DOI: 10.1167/iovs.15-18780

PubMed ID: 27096756

SO-VID: 4fd35bfb-28ed-462d-b329-cb30afe484f8

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