Correlation between intraluminal oxygen gradient and radial partitioning of intestinal microbiota.

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Abstract

The gut microbiota is a complex and densely populated community in a dynamic environment determined by host physiology. We investigated how intestinal oxygen levels affect the composition of the fecal and mucosally adherent microbiota.

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Author and article information

Journal

Journal ID (iso-abbrev): Gastroenterology

Title: Gastroenterology

Publisher: Elsevier BV

ISSN (Electronic): 1528-0012

ISSN (Print): 0016-5085

Publication date (Electronic): Nov 2014

Volume: 147

Issue: 5

Affiliations

[1 ] Division of Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

[2 ] Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

[3 ] Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

[4 ] Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

[5 ] Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; Division of Gastroenterology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

[6 ] Department of Emergency Medicine, University of Maryland, Baltimore, Maryland.

[7 ] Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address: vinograd@mail.med.upenn.edu.

[8 ] Division of Gastroenterology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address: gdwu@mail.med.upenn.edu.

Article

Publisher Item ID: S0016-5085(14)00916-0 Mid ID: NIHMS615453

DOI: 10.1053/j.gastro.2014.07.020

PMC ID: 4252572

PubMed ID: 25046162

SO-VID: 50dcb65f-21f7-4107-802f-85ef7dfd7e23

History

Keywords: Aerobic,Anaerobic,Microbe,Spatial Gradient of Oxygen

Data availability:

Keywords: Aerobic, Anaerobic, Microbe, Spatial Gradient of Oxygen

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