Preliminary Characterization of Extracellular Vesicles From Auditory HEI-OC1 Cells.

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Abstract

Isolate, purify, and characterize extracellular vesicles (EVs) obtained from auditory HEI-OC1 cells, and evaluate their suitability for intracochlear transport and delivery of pharmacological drugs and/or pro-resolution mediators of acute inflammatory processes.

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Journal

Journal ID (iso-abbrev): Ann Otol Rhinol Laryngol

Title: The Annals of otology, rhinology, and laryngology

Publisher: SAGE Publications

ISSN (Electronic): 1943-572X

ISSN (Print): 0003-4894

Publication date (Electronic): June 2019

Volume: 128

Issue: 6_suppl

Affiliations

[1 ] 1 Department of Head and Neck Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

[2 ] 2 Pasarow Mass Spectrometry Laboratory, Jane and Terry Semel Institute for Neuroscience and Human Behavior and Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

Article

DOI: 10.1177/0003489419836226

PubMed ID: 31092033

SO-VID: 5268d8eb-3910-4b11-84e4-5cc5087f64d1

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Keywords: intracochlear drug delivery,extracellular vesicles,HEI-OC1 cells,drug nanocarriers,proteomics

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Keywords: intracochlear drug delivery, extracellular vesicles, HEI-OC1 cells, drug nanocarriers, proteomics

Preliminary Characterization of Extracellular Vesicles From Auditory HEI-OC1 Cells.

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