Noemi D’Atanasio:
ORCID: http://orcid.org/0000-0003-0507-5717
Role: ConceptualizationRole: Project administrationRole: Writing – original draft
Alessandra Capezzone de Joannon: Role: Investigation
Laura Di Sante: Role: Resources
Giorgina Mangano: Role: Investigation
Rosella Ombrato: Role: Writing – original draft
Marco Vitiello: Role: Resources
Cristina Bartella: Role: Resources
Gabriele Magarò: Role: Resources
Federica Prati: Role: Writing – review & editing
Claudio Milanese: Role: ConceptualizationRole: SupervisionRole: Writing – original draftRole: Writing
– review & editing
Carla Vignaroli: Role: ConceptualizationRole: Writing – original draft
Francesco Paolo Di Giorgio: Role: Conceptualization
Serena Tongiani: Role: Supervision
Prabagaran Narayanasamy: Role: Editor
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
19
February
2020
Publication date Collection: 2020
Volume: 15
Issue: 2
Electronic Location Identifier: e0228509
Affiliations
[1
]
Angelini RR&D (Regulatory, Research & Development)–Angelini S.p.A., S. Palomba-Pomezia
(Rome), Italy
[2
]
Department of Life and Environmental Sciences, Polytechnic University of Marche, Ancona,
Italy
University of Nebraska Medical Center, UNITED STATES
Author notes
Competing Interests: The authors have read the journal's policy and the authors of this manuscript have
the following competing interests: NDA, ACJ, GaM, RO, MV, CB, GM, CM, FPDG and ST
are employees of Angelini S.p.A. LDS reports a grant in the context of the EUREKA
project co-funded by Angelini S.p.A. and by Regione Marche, Universita Politecnica
delle Marche (UNIVPM - Decreti Rettorali no. 740 July 2013 and no. 812 September 2013).
The authors would like to declare the following patents/patent applications associated
with this research: ACJ, GaM, RO and GM are inventors in patent WO2017/211759Al pending.
This does not alter our adherence to PLOS ONE policies on sharing data and materials.
Author information
Article
Publisher ID:
PONE-D-19-21722
DOI: 10.1371/journal.pone.0228509
PMC ID: 7029851
PubMed ID: 32074119
SO-VID: 53c9bb08-6da9-4290-9d17-f2e04d4f1825
Copyright © © 2020 D’Atanasio et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by: EUREKA
Award ID: UNIVPM – Decreti Rettorali no. 740 July 2013 and no. 812 September 2013
Award Recipient
:
Laura Di Sante
This work was funded by Angelini S.p.A. Angelini S.p.A. provided support in the form
of salaries for NDA, ACJ, GM, RO, MV, CB, GM, CM, FPDG and ST. LDS was supported by
a grant in the context of the EUREKA project co-funded by Angelini S.p.A. and by Regione
Marche, Universita Politecnica delle Marche (UNIVPM - Decreti Rettorali no. 740 July
2013 and no. 812 September 2013). The specific roles of these authors are articulated
in the "author contributions" section. The funder had a role in the study design,
data collection and analysis, decision to publish and preparation of the manuscript
through the provision of expert decision-making input from the preclinical management
teams.
Subject:
Research Article
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Bacteria
Subject:
Staphylococcus
Subject:
Staphylococcus Aureus
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Medical Microbiology
Subject:
Microbial Pathogens
Subject:
Bacterial Pathogens
Subject:
Staphylococcus
Subject:
Staphylococcus Aureus
Subject:
Medicine and Health Sciences
Subject:
Pathology and Laboratory Medicine
Subject:
Pathogens
Subject:
Microbial Pathogens
Subject:
Bacterial Pathogens
Subject:
Staphylococcus
Subject:
Staphylococcus Aureus
Subject:
Medicine and Health Sciences
Subject:
Pharmacology
Subject:
Drugs
Subject:
Antimicrobials
Subject:
Antibacterials
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Microbial Control
Subject:
Antimicrobials
Subject:
Antibacterials
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Microbial Control
Subject:
Antimicrobial Resistance
Subject:
Medicine and Health Sciences
Subject:
Pharmacology
Subject:
Antimicrobial Resistance
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Microbial Control
Subject:
Antimicrobial Resistance
Subject:
Antibiotic Resistance
Subject:
Medicine and Health Sciences
Subject:
Pharmacology
Subject:
Antimicrobial Resistance
Subject:
Antibiotic Resistance
Subject:
Medicine and Health Sciences
Subject:
Pharmacology
Subject:
Drugs
Subject:
Antimicrobials
Subject:
Antibiotics
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Microbial Control
Subject:
Antimicrobials
Subject:
Antibiotics
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Mutation
Subject:
Point Mutation
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Bacteriology
Subject:
Gram Negative Bacteria
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Medical Microbiology
Subject:
Microbial Pathogens
Subject:
Bacterial Pathogens
Subject:
Neisseria Gonorrhoeae
Subject:
Medicine and Health Sciences
Subject:
Pathology and Laboratory Medicine
Subject:
Pathogens
Subject:
Microbial Pathogens
Subject:
Bacterial Pathogens
Subject:
Neisseria Gonorrhoeae
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Bacteria
Subject:
Neisseria
Subject:
Neisseria Gonorrhoeae