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      Bariatric Surgery in Adolescents: To Do or Not to Do?

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          Abstract

          Pediatric obesity is a multifaceted disease that can impact physical and mental health. It is a complex condition that interweaves biological, developmental, environmental, behavioral, and genetic factors. In most cases lifestyle and behavioral modification as well as medical treatment led to poor short-term weight reduction and long-term failure. Thus, bariatric surgery should be considered in adolescents with moderate to severe obesity who have previously participated in lifestyle interventions with unsuccessful outcomes. In particular, laparoscopic sleeve gastrectomy is considered the most commonly performed bariatric surgery worldwide. The procedure is safe and feasible. The efficacy of this weight loss surgical procedure has been demonstrated in pediatric age. Nevertheless, there are barriers at the patient, provider, and health system levels, to be removed. First and foremost, more efforts must be made to prevent decline in nutritional status that is frequent after bariatric surgery, and to avoid inadequate weight loss and weight regain, ensuring successful long-term treatment and allowing healthy growth. In this narrative review, we considered the rationale behind surgical treatment options, outcomes, and clinical indications in adolescents with severe obesity, focusing on LSG, nutritional management, and resolution of metabolic comorbidities.

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          Clinical Practice Guideline for Screening and Management of High Blood Pressure in Children and Adolescents

          These pediatric hypertension guidelines are an update to the 2004 "Fourth Report on the Diagnosis, Evaluation, and Treatment of High Blood Pressure in Children and Adolescents." Significant changes in these guidelines include (1) the replacement of the term "prehypertension" with the term "elevated blood pressure," (2) new normative pediatric blood pressure (BP) tables based on normal-weight children, (3) a simplified screening table for identifying BPs needing further evaluation, (4) a simplified BP classification in adolescents ≥13 years of age that aligns with the forthcoming American Heart Association and American College of Cardiology adult BP guidelines, (5) a more limited recommendation to perform screening BP measurements only at preventive care visits, (6) streamlined recommendations on the initial evaluation and management of abnormal BPs, (7) an expanded role for ambulatory BP monitoring in the diagnosis and management of pediatric hypertension, and (8) revised recommendations on when to perform echocardiography in the evaluation of newly diagnosed hypertensive pediatric patients (generally only before medication initiation), along with a revised definition of left ventricular hypertrophy. These guidelines include 30 Key Action Statements and 27 additional recommendations derived from a comprehensive review of almost 15 000 published articles between January 2004 and July 2016. Each Key Action Statement includes level of evidence, benefit-harm relationship, and strength of recommendation. This clinical practice guideline, endorsed by the American Heart Association, is intended to foster a patient- and family-centered approach to care, reduce unnecessary and costly medical interventions, improve patient diagnoses and outcomes, support implementation, and provide direction for future research.
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            Extended international (IOTF) body mass index cut-offs for thinness, overweight and obesity : Extended international BMI cut-offs

            The international (International Obesity Task Force; IOTF) body mass index (BMI) cut-offs are widely used to assess the prevalence of child overweight, obesity and thinness. Based on data from six countries fitted by the LMS method, they link BMI values at 18 years (16, 17, 18.5, 25 and 30 kg m(-2)) to child centiles, which are averaged across the countries. Unlike other BMI references, e.g. the World Health Organization (WHO) standard, these cut-offs cannot be expressed as centiles (e.g. 85th). To address this, we averaged the previously unpublished L, M and S curves for the six countries, and used them to derive new cut-offs defined in terms of the centiles at 18 years corresponding to each BMI value. These new cut-offs were compared with the originals, and with the WHO standard and reference, by measuring their prevalence rates based on US and Chinese data. The new cut-offs were virtually identical to the originals, giving prevalence rates differing by < 0.2% on average. The discrepancies were smaller for overweight and obesity than for thinness. The international and WHO prevalences were systematically different before/after age 5. Defining the international cut-offs in terms of the underlying LMS curves has several benefits. New cut-offs are easy to derive (e.g. BMI 35 for morbid obesity), and they can be expressed as BMI centiles (e.g. boys obesity = 98.9th centile), allowing them to be compared with other BMI references. For WHO, median BMI is relatively low in early life and high at older ages, probably due to its method of construction. © 2012 The Authors. Pediatric Obesity © 2012 International Association for the Study of Obesity.
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              Expert panel on integrated guidelines for cardiovascular health and risk reduction in children and adolescents: summary report.

              , (2011)
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                Author and article information

                Contributors
                Role: Academic Editor
                Journal
                Children (Basel)
                Children (Basel)
                children
                Children
                MDPI
                2227-9067
                27 May 2021
                June 2021
                : 8
                : 6
                : 453
                Affiliations
                [1 ]Pediatric and Adolescent Unit, Department of Internal Medicine, University of Pavia, 27100 Pavia, Italy; valeria.calcaterra@ 123456unipv.it
                [2 ]Pediatric Department, “V. Buzzi” Children’s Hospital, 20154 Milan, Italy; elvira.verduci@ 123456unimi.it (E.V.); alessandra.bosetti@ 123456asst-fbf-sacco.it (A.B.); GianVincenzo.Zuccotti@ 123456unimi.it (G.Z.)
                [3 ]Clinical Nutrition and Dietetics Service, Unit of Internal Medicine and Endocrinology, ICS Maugeri IRCCS, 27100 Pavia, Italy; hellas.cena@ 123456unipv.it (H.C.); Debora.porri01@ 123456universitadipavia.it (D.P.)
                [4 ]Laboratory of Dietetics and Clinical Nutrition, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, 27100 Pavia, Italy
                [5 ]Pediatric Surgery Department, “V. Buzzi” Children’s Hospital, 20154 Milan, Italy; francesca.destro@ 123456asst-fbf-sacco.it (F.D.); elettra.vestri@ 123456asst-fbf-sacco.it (E.V.)
                [6 ]Pediatric Unit, Fond. IRCCS Policlinico S. Matteo and University of Pavia, 27100 Pavia, Italy; corrado.regalbuto01@ 123456universitadipavia.it (C.R.); fede90vinci@ 123456gmail.com (F.V.)
                [7 ]Department of Health Sciences, University of Milan, 20146 Milan, Italy
                [8 ]“L. Sacco” Department of Biomedical and Clinical Science, University of Milan, 20146 Milan, Italy
                [9 ]Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA; fstanford@ 123456mgh.harvard.edu
                Author notes
                Author information
                https://orcid.org/0000-0002-2137-5974
                https://orcid.org/0000-0002-5752-6199
                https://orcid.org/0000-0002-3327-5057
                https://orcid.org/0000-0003-2111-3111
                https://orcid.org/0000-0002-2795-9874
                https://orcid.org/0000-0003-4616-533X
                Article
                children-08-00453
                10.3390/children8060453
                8204230
                34072065
                56840388-6116-4566-862d-82db3f6cbdcd
                © 2021 by the authors.

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( https://creativecommons.org/licenses/by/4.0/).

                History
                : 09 April 2021
                : 25 May 2021
                Categories
                Review

                pediatric obesity,bariatric surgery,adolescents,nutritional status,weight loss,laparoscopic sleeve gastrectomy,multi-disciplinarity,complications

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