8
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: not found
      • Article: not found

      Neurosarcoidosis: clinical presentations and course in 50 patients

      Acta Neurologica Scandinavica

      Wiley

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Fifty consecutive patients with neurosarcoidosis were evaluated retrospectively. Sarcoidosis presented first with neurologic signs in 24 patients (48%), but systemic symptoms developed later in all but five. Main neurologic involvements were central nervous system lesions in 33 patients (66%), cranial nerve paresis in 12 (24%), and peripheral nerve lesions in five patients (10%). Seventeen patients (34%) had more than one type of neurologic involvement. Routine cerebrospinal fluid (CSF) parameters showed unspecific abnormalities in 35 patients (70%). CSF angiotensin converting enzyme was elevated in 18 of 31 patients (58%). Brain computerized tomography was abnormal in 13 of 32 patients (41%). Visual and brainstem evoked potentials were abnormal in ten (43%) and eight (35%) of 23 patients, respectively, suggesting subclinical lesions in 13 patients. Neurologic signs improved in 24 patients (48%), were stable in 11 (22%), and progressed in 15 patients (30%). Six patients died. Cranial nerve lesions improved most often. Course of neurologic involvements was similar in acute or subacute and chronic sarcoidosis. The effect of steroid treatment was inconsistent.

          Related collections

          Most cited references 26

          • Record: found
          • Abstract: not found
          • Article: not found

          Course and prognosis of sarcoidosis around the world.

            Bookmark
            • Record: found
            • Abstract: not found
            • Article: not found

            Manifestations of sarcoidosis

              Bookmark
              • Record: found
              • Abstract: not found
              • Article: not found

              Sarcoidosis: A Clinicopathologic Review of Three Hundred Cases, Including Twenty-Two Autopsies

                Bookmark

                Author and article information

                Journal
                Acta Neurologica Scandinavica
                Wiley
                00016314
                16000404
                March 1986
                January 29 2009
                : 73
                : 3
                : 283-290
                Article
                10.1111/j.1600-0404.1986.tb03277.x
                3716768
                © 2009

                Comments

                Comment on this article