Comparison of Targeted vs Random Biopsies for Surveillance of Ulcerative Colitis-Associated Colorectal Cancer.

Watanabe, Toshiaki; Ajioka, Yoichi; Mitsuyama, Keiichi; Watanabe, Kenji; Hanai, Hiroyuki; Nakase, Hiroshi; Kunisaki, Reiko; Matsuda, Keiji; Iwakiri, Ryuichi; Hida, Nobuyuki; Tanaka, Shinji; Takeuchi, Yoshiaki; Ohtsuka, Kazuo; Murakami, Kazunari; Kobayashi, Kiyonori; Iwao, Yasushi; Nagahori, Masakazu; Iizuka, Bunei; Hata, Keisuke; Igarashi, Masahiro; Hirata, Ichiro; Kudo, Shin-Ei; Matsumoto, Takayuki; Ueno, Fumiaki; Watanabe, Gen; Ikegami, Masahiro; Ito, Yoko; Oba, Koji; Inoue, Eisuke; Tomotsugu, Naoki; Takebayashi, Toru; Sugihara, Kenichi; Suzuki, Yasuo; Watanabe, Mamoru; Hibi, Toshifumi

doi:10.1053/j.gastro.2016.08.002

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Comparison of Targeted vs Random Biopsies for Surveillance of Ulcerative Colitis-Associated Colorectal Cancer.

Author(s): Toshiaki Watanabe, Yoichi Ajioka, Keiichi Mitsuyama, Kenji Watanabe, Hiroyuki Hanai, Hiroshi Nakase, Reiko Kunisaki, Keiji Matsuda, Ryuichi Iwakiri, Nobuyuki Hida, Shinji Tanaka, Yoshiaki Takeuchi, Kazuo Ohtsuka, Kazunari Murakami, Kiyonori Kobayashi, Yasushi Iwao, Masakazu Nagahori, Bunei Iizuka, Keisuke Hata, Masahiro Igarashi, Ichiro Hirata, Shin-Ei Kudo, Takayuki Matsumoto, Fumiaki Ueno, Gen Watanabe, Masahiro Ikegami, Yoko Ito, Koji Oba, Eisuke Inoue, Naoki Tomotsugu, Toru Takebayashi, Kenichi Sugihara, Yasuo Suzuki, Mamoru Watanabe, Toshifumi Hibi

Publication date: 2016-12-01

Journal: Gastroenterology

Publisher: Elsevier BV

Keywords: IBD, Dysplasia, Colonoscopy, Random Biopsy

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Abstract

A random biopsy is recommended for surveillance of ulcerative colitis (UC)-associated colorectal cancer. However, a targeted biopsy might be more effective. We conducted a randomized controlled trial to compare rates of neoplasia detection by targeted vs random biopsies in patients with UC.