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      Arterial and Venous Circulation in the Ischaemic Myocardium in Young Animals

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          Abstract

          The descending ramus of the left coronary artery was ligated below the branching off of the septal artery in 15 (2 to 4-month-old) puppies, and 10 and 11 min later retrograde blood flow was measured in the peripheral stump and blood flow in the anterior interventricular vein. Veno-venous anastomoses After ligating the descending ramus 8.7–42% of the initial amount of blood flowed through the ischaemic area in the anterior interventricular vein. The origin of the blood is two-fold: arterial, via artero-arterial anastomoses, and venous, via veno-venous anastomoses. Retrograde blood flow in the peripheral stump of the descending ramus was 0–0.45 ml/min. After ligating the descending ramus in puppies 73–99% (average 91%) of the total blood flow from the infarcted area, measured in the anterior interventricular vein, can be attributed to veno-venous anastomoses. In two puppies arterial flow was zero.The injection of the vessels showed insignificantly formed arterio-arterial anastomoses in contrast to the network of veno-venous anastomoses. Both the blood flow values and the morphological findings are evidence that in puppies it is mostly venous blood which flows through the ischaemic area. The proportion is greater (91%) than in adult dogs (47%).

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          Author and article information

          Journal
          JVR
          J Vasc Res
          10.1159/issn.1018-1172
          Journal of Vascular Research
          S. Karger AG
          1018-1172
          1423-0135
          1970
          1970
          18 September 2008
          : 7
          : 2
          : 77-83
          Affiliations
          Institute of Anatomy, Medical Faculty, Charles University, Prague
          Article
          157822 Angiologica 1970;7:77–83
          10.1159/000157822
          5aff64e1-7626-4087-9295-0d4a755e169d
          © 1970 S. Karger AG, Basel

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          History
          Page count
          Pages: 7
          Categories
          Paper

          General medicine,Neurology,Cardiovascular Medicine,Internal medicine,Nephrology
          Proportion of blood flow in veno-venous and arterio- arterial anastomoses,Ligation of descending ramus of coronary artery,Blood flow through ischemic area,Arterio-arterial anastomoses

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