Peripheral, Interictal Serum S100B Levels are Not Increased in Chronic Migraine Patients.

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Abstract

The trigemino-vascular system (TVS) plays a key role in migraine pathophysiology. Glial cells are abundant in the TVS system and mainly in the trigeminal ganglion. S100B protein is a calcium-binding protein, found in the cytoplasm of glial cells in the central nervous system, which is released in response to inflammatory stimuli. Previous works analyzing S100B in migraineurs have offered contradictory results.

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Journal

Journal ID (iso-abbrev): Headache

Title: Headache

Publisher: Wiley

ISSN (Electronic): 1526-4610

ISSN (Print): 0017-8748

Publication date (Electronic): Sep 2020

Volume: 60

Issue: 8

Affiliations

[1 ] Service of Neurology, University Hospital Central de Asturias, Oviedo, Spain.

[2 ] Biomedical Data Sciences Department, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.

[3 ] Service of Neurology, University Hospital Marqués de Valdecilla, IDIVAL and University of Cantabria, Santander, Spain.

Article

DOI: 10.1111/head.13919

PubMed ID: 32804418

SO-VID: 5c99d1a6-4167-4d6d-977f-dedb3a92c235

History

Keywords: S100B,chronic migraine,trigemino-vascular system

Data availability:

Keywords: S100B, chronic migraine, trigemino-vascular system

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