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      Trends, structural changes, and assessment of time series models for forecasting hospital discharge due to death at a Mexican tertiary care hospital

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          Abstract

          Background

          Data on hospital discharges can be used as a valuable instrument for hospital planning and management. The quantification of deaths can be considered a measure of the effectiveness of hospital intervention, and a high percentage of hospital discharges due to death can be associated with deficiencies in the quality of hospital care.

          Objective

          To determine the overall percentage of hospital discharges due to death in a Mexican tertiary care hospital from its opening, to describe the characteristics of the time series generated from the monthly percentage of hospital discharges due to death and to make and evaluate predictions.

          Methods

          This was a retrospective study involving the medical records of 81,083 patients who were discharged from a tertiary care hospital from April 2007 to December 2019 (first 153 months of operation). The records of the first 129 months (April 2007 to December 2017) were used for the analysis and construction of the models (training dataset). In addition, the records of the last 24 months (January 2018 to December 2019) were used to evaluate the predictions made (test dataset). Structural change was identified (Chow test), ARIMA models were adjusted, predictions were estimated with and without considering the structural change, and predictions were evaluated using error indices (MAE, RMSE, MAPE, and MASE).

          Results

          The total percentage of discharges due to death was 3.41%. A structural change was observed in the time series (March 2009, p>0.001), and ARIMA(0,0,0)(1,1,2) 12 with drift models were adjusted with and without consideration of the structural change. The error metrics favored the model that did not consider the structural change (MAE = 0.63, RMSE = 0.81, MAPE = 25.89%, and MASE = 0.65).

          Conclusion

          Our study suggests that the ARIMA models are an adequate tool for future monitoring of the monthly percentage of hospital discharges due to death, allowing us to detect observations that depart from the described trend and identify future structural changes.

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          Most cited references24

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          Tests of Equality Between Sets of Coefficients in Two Linear Regressions

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            Regional alcohol consumption and alcohol-related mortality in Great Britain: novel insights using retail sales data

            Background Regional differences in population levels of alcohol-related harm exist across Great Britain, but these are not entirely consistent with differences in population levels of alcohol consumption. This incongruence may be due to the use of self-report surveys to estimate consumption. Survey data are subject to various biases and typically produce consumption estimates much lower than those based on objective alcohol sales data. However, sales data have never been used to estimate regional consumption within Great Britain (GB). This ecological study uses alcohol retail sales data to provide novel insights into regional alcohol consumption in GB, and to explore the relationship between alcohol consumption and alcohol-related mortality. Methods Alcohol sales estimates derived from electronic sales, delivery records and retail outlet sampling were obtained. The volume of pure alcohol sold was used to estimate per adult consumption, by market sector and drink type, across eleven GB regions in 2010–11. Alcohol-related mortality rates were calculated for the same regions and a cross-sectional correlation analysis between consumption and mortality was performed. Results Per adult consumption in northern England was above the GB average and characterised by high beer sales. A high level of consumption in South West England was driven by on-trade sales of cider and spirits and off-trade wine sales. Scottish regions had substantially higher spirits sales than elsewhere in GB, particularly through the off-trade. London had the lowest per adult consumption, attributable to lower off-trade sales across most drink types. Alcohol-related mortality was generally higher in regions with higher per adult consumption. The relationship was weakened by the South West and Central Scotland regions, which had the highest consumption levels, but discordantly low and very high alcohol-related mortality rates, respectively. Conclusions This study provides support for the ecological relationship between alcohol-related mortality and alcohol consumption. The synthesis of knowledge from a combination of sales, survey and mortality data, as well as primary research studies, is key to ensuring that regional alcohol consumption, and its relationship with alcohol-related harms, is better understood.
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              strucchange: AnRPackage for Testing for Structural Change in Linear Regression Models

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                Author and article information

                Contributors
                Role: ConceptualizationRole: Data curationRole: Formal analysisRole: InvestigationRole: MethodologyRole: Project administrationRole: SoftwareRole: SupervisionRole: ValidationRole: VisualizationRole: Writing – original draftRole: Writing – review & editing
                Role: ConceptualizationRole: Formal analysisRole: MethodologyRole: Project administrationRole: SupervisionRole: ValidationRole: Writing – review & editing
                Role: Data curationRole: Formal analysisRole: InvestigationRole: SoftwareRole: VisualizationRole: Writing – original draft
                Role: Formal analysisRole: InvestigationRole: SoftwareRole: VisualizationRole: Writing – original draft
                Role: Formal analysisRole: InvestigationRole: SoftwareRole: VisualizationRole: Writing – original draft
                Role: ConceptualizationRole: Formal analysisRole: MethodologyRole: Project administrationRole: SupervisionRole: ValidationRole: Writing – review & editing
                Role: Editor
                Journal
                PLoS One
                PLoS One
                plos
                plosone
                PLoS ONE
                Public Library of Science (San Francisco, CA USA )
                1932-6203
                8 March 2021
                2021
                : 16
                : 3
                : e0248277
                Affiliations
                [1 ] Department of Research, Hospital Regional de Alta Especialidad del Bajío, León, Guanajuato, México
                [2 ] Programa de Biotecnología, Universidad de Guanajuato, Celaya, Guanajuato, México
                [3 ] CONACYT-Instituto Nacional de Salud Pública, Cuernavaca, Morelos, México
                South China University of Technology, CHINA
                Author notes

                Competing Interests: The authors have declared that no competing interests exist.

                Author information
                https://orcid.org/0000-0003-4287-9626
                https://orcid.org/0000-0002-9912-6097
                Article
                PONE-D-20-38228
                10.1371/journal.pone.0248277
                7939298
                33684171
                5d0f4e91-02bc-4669-b297-dbf4f9411e43
                © 2021 Rodea-Montero et al

                This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

                History
                : 15 December 2020
                : 23 February 2021
                Page count
                Figures: 6, Tables: 3, Pages: 16
                Funding
                The author(s) received no specific funding for this work.
                Categories
                Research Article
                Medicine and Health Sciences
                Health Care
                Health Care Facilities
                Hospitals
                Engineering and Technology
                Signal Processing
                Autocorrelation
                Research and Analysis Methods
                Mathematical and Statistical Techniques
                Statistical Methods
                Autocorrelation
                Physical Sciences
                Mathematics
                Statistics
                Statistical Methods
                Autocorrelation
                People and places
                Population groupings
                Ethnicities
                Latin American people
                Mexican People
                Biology and Life Sciences
                Population Biology
                Population Metrics
                Death Rates
                Medicine and Health Sciences
                Surgical and Invasive Medical Procedures
                Research and Analysis Methods
                Mathematical and Statistical Techniques
                Statistical Methods
                Forecasting
                Physical Sciences
                Mathematics
                Statistics
                Statistical Methods
                Forecasting
                Research and Analysis Methods
                Research Design
                Retrospective Studies
                Research and Analysis Methods
                Database and Informatics Methods
                Health Informatics
                Custom metadata
                All data underlying the findings are available in the Mexican General Directorate of Health Information website at: http://www.dgis.salud.gob.mx/contenidos/basesdedatos/da_egresoshosp_gobmx.html.

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                Uncategorized

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