49
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Plasmaféresis terapéutica, tipos, técnica e indicaciones en medicina interna: types, techniques and indications in internal medicine Translated title: Therapeutic plasma exchange

      other

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          La plasmaféresis es un procedimiento extracorpóreo, en el cual a partir de la sangre extraída del paciente se procede a separarla en sus componentes plasma y elementos celulares. Constituye una variedad de aféresis, y su objetivo principal es remover elementos específicos del plasma, los cuales se consideran que son mediadores de procesos patológicos. Existen dos métodos de plasmaféresis: plasmaféresis por centrifugación, el cual requiere de equipos complicados y de uso común en bancos de sangre, y plasmaféresis por filtración, la que se puede practicar también por equipos exclusivamente diseñados para ese propósito y que son de difícil obtención. La plasmaféresis por filtración con plasmafiltros adaptados a máquinas de hemodiálisis es un alternativa terapéutica de fácil utilización, bajo costo y con la posibilidad de ser practicada por el personal médico y paramédico que labora en unidades renales. Con base en nuestra experiencia de 16 años en la práctica de este procedimiento, presentamos nuestras recomendaciones de cómo llevar a cabo el procedimiento, detalles técnicos y acercamiento al manejo de las complicaciones que se presentan durante el mismo.

          Translated abstract

          Plasmapheresis is an extracorporeal procedure by which the patient’s blood is separated into its components: plasma and cellular elements. It represents a variety of apheresis, and its main objective is to remove specific elements from plasma, which are considered mediators of pathological processes. There are 2 methods of plasmapheresis: plasmapheresis with centrifugation devices, which requires complicated equipment commonly used in blood banks, and plasmapheresis with highly permeable filter, which is also carried out in equipment exclusively designed for the purpose. This equipment is difficult to obtain. Plasmapheresis with highly permeable filters adapted to standard hemodialysis equipment is a simple, low-cost therapeutic option that can be put into practice by the medical and paramedical staff working in renal units. Based on our experience of 16 years practicing this procedure, we present our recommendations on how to perform it, as well as technical details and an approach on how to handle the complications that may arise.

          Related collections

          Most cited references16

          • Record: found
          • Abstract: found
          • Article: not found

          Complications of therapeutic plasma exchange: experience with 4857 treatments.

          Plasma exchange (PE) is a technique of extracorporeal blood purification which removes large molecular weight substances from plasma. The Department of Dialysis, Zagreb University Hospital Center's database, which includes data on 509 patients, or 4857 PE treatments, was retrospectively analyzed to test the safety of PE. A total of 231 adverse reactions were recorded (4.75% of treatments). The most common complications were paresthesias (2.7%), hematoma at the puncture site (2.4%), clotting (1.7%), mild to moderate allergic reactions (urticaria; 1.6%) and bleeding (0.06%). True anaphylactoid reactions were recorded in five procedures. The incidence of severe, potentially life-threatening adverse reactions was 0.12%. The prophylactic use of calcium and potassium was responsible for a low incidence of electrolyte disturbances. There was no lethal outcome associated with PE. When carried out by experienced staff, PE is a relatively safe procedure. The use of fresh frozen plasma is associated with a higher rate of adverse reactions.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            The risk of transfusion-transmitted viral infections. The Retrovirus Epidemiology Donor Study.

            Accurate estimates of the risk of transfusion-transmitted infectious disease are essential for monitoring the safety of the blood supply and evaluating the potential effect of new screening tests. We estimated the risk of transmitting the human Immuno-deficiency virus (HIV), the human T-cell lymphotropic virus (HTLV), the hepatitis C virus (HCV), and the hepatitis B virus (HBV) from screened blood units donated during the window period following a recent, undetected infection. Using data on 586,507 persons who each donated blood more than once between 1991 and 1993 at five blood centers (for a total of 2,318,356 allogeneic blood donations), we calculated the incidence rates of seroconversion among those whose donations passed all the screening tests used. We adjusted these rates for the estimated duration of the infectious window period for each virus. We then estimated the further reductions in risk that would result from the use of new and more sensitive viral-antigen or nucleic acid screening tests. Among donors whose units passed all screening tests, the risks of giving blood during an infectious window period were estimated as follows: for HIV, 1 in 493,000 (95 percent confidence interval, 202,000 to 2,778,000); for HTLV, 1 in 641,000 (256,000 to 2,000,000); for HCV, 1 in 103,000 (28,000 to 288,000); and for HBV, 1 in 63,000 (31,000 to 147,000). HBV and HCV accounted for 88 percent of the aggregate risk of 1 in 34,000. New screening tests that shorten the window periods for the four viruses should reduce the risks by 27 to 72 percent. The risk of transmitting HIV, HTLV, HCV, or HBV infection by the transfusion of screened blood is very small, and new screening tests will reduce the risk even further.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Guidelines on the use of therapeutic apheresis in clinical practice: evidence-based approach from the Apheresis Applications Committee of the American Society for Apheresis.

              The American Society for Apheresis (ASFA) Apheresis Applications Committee is charged with a review and categorization of indications for therapeutic apheresis. This elaborate process had been undertaken every 7 years resulting in three prior publications in 1986, 1993, and 2000 of "The ASFA Special Issues." This article is the integral part of the Fourth ASFA Special Issue. The Fourth ASFA Special Issue is significantly modified in comparison to the previous editions. A new concept of a fact sheet has been introduced. The fact sheet succinctly summarizes the evidence for the use of therapeutic apheresis. A detailed description of the fact sheet is provided. The article consists of 53 fact sheets devoted to each disease entity currently categorized by the ASFA. Categories I, II, and III are defined as previously in the Third Special Issue. However, a few new therapeutic apheresis modalities, not yet approved in the United States or are currently in clinical trials, have been assigned category P (pending) by the ASFA Clinical Categories Subcommittee. The diseases assigned to category IV are discussed in a separate article in this issue.
                Bookmark

                Author and article information

                Journal
                amc
                Acta Medica Colombiana
                Acta Med Colomb
                Asociacion Colombiana de Medicina Interna (Bogotá, Distrito Capital, Colombia )
                0120-2448
                March 2009
                : 34
                : 1
                : 23-32
                Affiliations
                [03] Manizales orgnameRTS Ltda Colombia
                [02] Manizales orgnameRTS Ltda Colombia
                [01] Manizales orgnameRTS Ltda Colombia
                Article
                S0120-24482009000100005 S0120-2448(09)03400105
                5e1e28db-d524-4207-ae53-250e207ea8f3

                This work is licensed under a Creative Commons Attribution 4.0 International License.

                History
                : 30 January 2009
                : 15 June 2008
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 18, Pages: 10
                Product

                SciELO Colombia

                Categories
                Actualizaciones

                plasmaféresis,aféresis,equipos de hemodiálisis,técnica,complicaciones,apheresis,hemodialysis equipment,plasmapheresis,technical,complications

                Comments

                Comment on this article