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      Primary care for patients with respiratory tract infection before and early on in the COVID-19 pandemic: an observational study in 16 European countries

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          Abstract

          Objective

          To describe primary health care (consultation characteristics and management) for patients contacting their general practitioner (GP) with a respiratory tract infection (RTI) early on in the COVID-19 pandemic in contrasting European countries, with comparison to prepandemic findings.

          Setting

          Primary care in 16 countries (79 practices), when no routine SARS-CoV-2 testing was generally available.

          Design and participants

          Before (n=4376) and early in the pandemic (n=3301), patients with RTI symptoms were registered in this prospective audit study.

          Outcome measures

          Consultation characteristics (type of contact and use of PPE) and management characteristics (clinical assessments, diagnostic testing, prescribing, advice and referral) were registered. Differences in these characteristics between countries and between pandemic and prepandemic care are described.

          Results

          Care for patients with RTIs rapidly switched to telephone/video consultations (10% in Armenia, 91% in Denmark), and when consultations were face-to-face, GPs used PPE during 97% (95% CI 96% to 98%) of contacts. Laboratory testing for SARS-CoV-2 in primary care patients with RTIs was rapidly implemented in Denmark (59%) and Germany (31%), while overall testing for C reactive protein decreased. The proportion of patients prescribed antibiotics varied considerably between countries (3% in Belgium, 48% in UK) and was lower during the pandemic compared with the months before, except for Greece, Poland and UK. GPs provided frequent and varied COVID-related advice and more frequently scheduled a follow-up contact (50%, 95% CI 48% to 52%). GPs reported a slightly higher degree of confidence in the likely effectiveness of their management in face-to-face (73% (very) confident, 95% CI 71% to 76%) than in virtual consultations (69%, 95% CI 67% to 71%).

          Conclusions

          Despite between-country variation in consultation characteristics, access to SARS-CoV-2 laboratory testing and medication prescribing, GPs reported a high degree of confidence in managing their patients with RTIs in the emerging pandemic. Insight in the highly variable pandemic responses, as measured in this multicountry audit, can aid in fine-tuning national action and in coordinating a pan-European response during future pandemic threats.

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          Most cited references17

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          A Comprehensive Literature Review on the Clinical Presentation, and Management of the Pandemic Coronavirus Disease 2019 (COVID-19)

          Coronavirus disease 2019 (COVID-19) is a declared global pandemic. There are multiple parameters of the clinical course and management of the COVID-19 that need optimization. A hindrance to this development is the vast amount of misinformation present due to scarcely sourced manuscript preprints and social media. This literature review aims to presents accredited and the most current studies pertaining to the basic sciences of SARS-CoV-2, clinical presentation and disease course of COVID-19, public health interventions, and current epidemiological developments. The review on basic sciences aims to clarify the jargon in virology, describe the virion structure of SARS-CoV-2 and present pertinent details relevant to clinical practice. Another component discussed is the brief history on the series of experiments used to explore the origins and evolution of the phylogeny of the viral genome of SARS-CoV-2. Additionally, the clinical and epidemiological differences between COVID-19 and other infections causing outbreaks (SARS, MERS, H1N1) are elucidated. Emphasis is placed on evidence-based medicine to evaluate the frequency of presentation of various symptoms to create a stratification system of the most important epidemiological risk factors for COVID-19. These can be used to triage and expedite risk assessment. Furthermore, the limitations and statistical strength of the diagnostic tools currently in clinical practice are evaluated. Criteria on rapid screening, discharge from hospital and discontinuation of self-quarantine are clarified. Epidemiological factors influencing the rapid rate of spread of the SARS-CoV-2 virus are described. Accurate information pertinent to improving prevention strategies is also discussed. The penultimate portion of the review aims to explain the involvement of micronutrients such as vitamin C and vitamin D in COVID19 treatment and prophylaxis. Furthermore, the biochemistry of the major candidates for novel therapies is briefly reviewed and a summary of their current status in the clinical trials is presented. Lastly, the current scientific data and status of governing bodies such as the Center of Disease Control (CDC) and the WHO on the usage of controversial therapies such as angiotensin-converting enzyme (ACE) inhibitors, nonsteroidal anti-inflammatory drugs (NSAIDs) (Ibuprofen), and corticosteroids usage in COVID-19 are discussed. The composite collection of accredited studies on each of these subtopics of COVID-19 within this review will enable clarification and focus on the current status and direction in the planning of the management of this global pandemic.
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            Impact of the COVID-19 pandemic on the core functions of primary care: will the cure be worse than the disease? A qualitative interview study in Flemish GPs

            Objectives The current COVID-19 pandemic, as well as the measures taken to control it, have a profound impact on healthcare. This study was set up to gain insights into the consequences of the COVID-19 outbreak on the core competencies of general practice, as they are experienced by general practitioners (GPs) on the frontline. Design, setting, participants We performed a descriptive study using semistructured interviews with 132 GPs in Flanders, using a topic list based on the WONCA definition of core competencies in general practice. Data were analysed qualitatively using framework analysis. Results Changes in practice management and in consultation strategies were quickly adopted. There was a major switch towards telephone triage and consults, for covid-related as well as for non-covid related problems. Patient-centred care is still a major objective. Clinical decision-making is largely focused on respiratory assessment and triage, and GPs feel that acute care is compromised, both by their own changed focus and by the fact that patients consult less frequently for non-covid problems. Chronic care is mostly postponed, and this will have consequences that will extend and become visible after the corona crisis. Through the holistic eyes of primary care, the current outbreak—as well as the measures taken to control it—will have a profound impact on psychological and socioeconomic well-being. This impact is already visible in vulnerable people and will continue to become clear in the medium and long terms. GPs think that they are at high risk of getting infected. Dropping out and being unable to contribute their part or becoming virus transmitters are reported to be greater concerns than getting ill themselves. Conclusions The current times have a profound impact on the core competences of primary care. Although the vast increase in patients soliciting medical help and the necessary separate covid and non-covid flows have been dealt with, GPs are worried about the continuity of regular care and the consequences of the anticovid measures. These may become a threat for the general health of the population and for the provision of primary healthcare in the near and distant future.
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              Lessons on the COVID-19 pandemic, for and by primary care professionals worldwide

              Abstract The COVID-19 pandemic has modified organisation and processes of primary care. In this paper, we aim to summarise experiences of international primary care systems. We explored personal accounts and findings in reporting on the early experiences from primary care during the pandemic, through the online Global Forum on Universal Health Coverage and Primary Health Care. During the early stage of the pandemic, primary care continued as the first point of contact to the health system but was poorly informed by policy makers on how to fulfil its role and ill equipped to provide care while protecting staff and patients against further spread of the infection. In many countries, the creativity and initiatives of local health professionals led to the introduction or extension of the use of telephone, e-mail and virtual consulting, and introduced triaging to separate ‘suspected’ COVID-19 from non-COVID-19 care. There were substantial concerns of collateral damage to the health of the population due to abandoned or postponed routine care. The pandemic presents important lessons to strengthen health systems through better connection between public health, primary care, and secondary care to cope better with future waves of this and other pandemics.
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                Author and article information

                Journal
                BMJ Open
                BMJ Open
                bmjopen
                bmjopen
                BMJ Open
                BMJ Publishing Group (BMA House, Tavistock Square, London, WC1H 9JR )
                2044-6055
                2021
                29 July 2021
                29 July 2021
                : 11
                : 7
                : e049257
                Affiliations
                [1 ]departmentJulius Center for Health Sciences and Primary Care , UMC Utrecht , Utrecht, The Netherlands
                [2 ]departmentNuffield Department of Primary Care Health Sciences , University of Oxford , Oxford, UK
                [3 ]departmentInstitute for Public Health , University of Copenhagen , Copenhagen, Denmark
                [4 ]departmentClinic of Social and Family Medicine , University of Crete , Heraklion, Greece
                [5 ]departmentFamily Medicine and Population Health , Universiteit Antwerpen , Antwerpen, Belgium
                [6 ]Balan Medfam SRL , Cluj Napoca, Romania
                [7 ]departmentInstitute of General Practice , Rostock University Medical Center , Rostock, Germany
                [8 ]departmentDépartement de Santé Publique , Centre Hospitalier Universitaire de Nice , Nice, France
                [9 ]departmentDepartment of Family Medicine Medical , University of Bialystok , Bialystok, Poland
                [10 ]Abbott Rapid Diagnostics Germany GmbH , Cologne, Germany
                [11 ]departmentMedicines Research Unit , Institut Universitari d'Investigació en Atenció Primària Jordi Gol (IDIAP Jordi Gol) , Barcelona, Spain
                [12 ]departmentGeneral Pediatrics , Wigmore Clinic Medical Center Yerevan , Yerevan, Armenia
                [13 ]National Center for Disease Control and Public Health , Tbilisi, Georgia
                [14 ]Drug Research Centre LLC , Balatonfüred, Hungary
                [15 ]departmentUniversity Clinic of Primary Medical Assistance , State University of Medicine 'N. Testemițanu' , Chişinǎu, the Republic of Moldova
                [16 ]departmentSchool of Medicine , NUI Galway , Galway, Ireland
                [17 ]NGO Academy of Family Medicine of Ukraine , Lviv, Ukraine
                [18 ]departmentMedical Microbiology, Vaccine and Infectious Diseases Institute (VAXINFECTIO) , University of Antwerp , Antwerp, Belgium
                Author notes
                [Correspondence to ] Dr Alike W van der Velden; a.w.vandervelden@ 123456umcutrecht.nl
                Author information
                http://orcid.org/0000-0002-9443-2837
                http://orcid.org/0000-0001-5957-6280
                http://orcid.org/0000-0002-1238-8052
                http://orcid.org/0000-0003-4960-2355
                http://orcid.org/0000-0002-6689-6466
                http://orcid.org/0000-0003-4470-1151
                http://orcid.org/0000-0002-6583-4300
                http://orcid.org/0000-0002-0102-3453
                Article
                bmjopen-2021-049257
                10.1136/bmjopen-2021-049257
                8326026
                34326052
                5ea3f9a1-dcc7-4693-8fa0-cf5a14fc70a6
                © Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

                This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See:  http://creativecommons.org/licenses/by-nc/4.0/.

                History
                : 11 February 2021
                : 07 July 2021
                Funding
                Funded by: Horizon 2020 research and innovation programme;
                Award ID: 101003589
                Funded by: Innovative Medicine Initiative 2 Joint Undertaking;
                Award ID: 820755
                Categories
                General practice / Family practice
                1506
                2474
                1696
                Original research
                Custom metadata
                unlocked

                Medicine
                covid-19,primary care,respiratory infections,audit,quality in healthcare
                Medicine
                covid-19, primary care, respiratory infections, audit, quality in healthcare

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