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      Partial Purification and Characterization of Lenticular S-Adenosylmethionine Synthetase

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          Abstract

          Lenticular S-adenosylmethionine synthetase has been partially purified and characterized. Lower levels of S-adenosylmethionine synthetase were detected by a sensitive radioactive assay procedure in the lenticular extract obtained from the pooled lenses of alloxan-treated rats 96 days of age as compared to the nontreated controls. With respect to chromatographic behavior and kinetic analysis, lenticular S-adenosylmethionine synthetase closely resembled that of the corresponding liver enzyme

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          Author and article information

          Journal
          ORE
          Ophthalmic Res
          10.1159/issn.0030-3747
          Ophthalmic Research
          S. Karger AG
          0030-3747
          1423-0259
          1982
          1982
          04 December 2009
          : 14
          : 1
          : 9-21
          Affiliations
          aDepartment of Pharmacology, University of Karachi; bDepartment of Biochemistry, Jinnah Postgraduate Medical Center, Karachi, Pakistan
          Article
          265169 Ophthalmic Res 1982;14:9–21
          10.1159/000265169
          7070760
          5fffefc3-0954-4990-b99c-ba08ec09a85c
          © 1982 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          : 20 October 1980
          : 15 January 1981
          Page count
          Pages: 13
          Categories
          Original Paper

          Vision sciences,Ophthalmology & Optometry,Pathology
          Enzyme purification,S-Adenosylmethionine synthetase,Alloxan treatmant,Lens,Rat

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