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      Neurocysticercosis a public health problem

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          Key Clinical Message

          Neurocysticercosis is a parasitic disease of the central nervous system that constitutes a public health problem in endemic regions. Here, we present a patient with epilepsy and cognitive impairment due to neurocysticercosis. A public health intervention could eradicate this disease in endemic regions such as Ecuador.

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          Clinical symptoms, diagnosis, and treatment of neurocysticercosis.

          The infection of the nervous system by the cystic larvae of Taenia solium (neurocysticercosis) is a frequent cause of seizure disorders. Neurocysticercosis is endemic or presumed to be endemic in many low-income countries. The lifecycle of the worm and the clinical manifestations of neurocysticercosis are well established, and CT and MRI have substantially improved knowledge of the disease course. Improvements in immunodiagnosis have further advanced comprehension of the pathophysiology of this disease. This knowledge has led to individualised treatment approaches that account for the involvement of parenchymal or extraparenchymal spaces, the number and form of parasites, and the extent of degeneration and associated inflammation. Clinical investigations are focused on development of effective treatments and reduction of side-effects induced by treatment, such as seizures, hydrocephalus, infarcts, and neuroinjury.
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            Antiepileptic drug therapy and recommendations for withdrawal in patients with seizures and epilepsy due to neurocysticercosis.

            Neurocysticercosis (NCC) is a leading causes of secondary epilepsy worldwide. There is increasing evidence on the epileptogenic role of NCC, and the presence of edema, calcified scars, gliosis and hippocampal sclerosis support this phenomenon.
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              Cysticercosis of the human nervous system

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                Author and article information

                Contributors
                patocorrea2010@yahoo.com
                Journal
                Clin Case Rep
                Clin Case Rep
                10.1002/(ISSN)2050-0904
                CCR3
                Clinical Case Reports
                John Wiley and Sons Inc. (Hoboken )
                2050-0904
                02 March 2017
                April 2017
                : 5
                : 4 ( doiID: 10.1002/ccr3.2017.5.issue-4 )
                : 543-544
                Affiliations
                [ 1 ] Department of Neurology at Carlos Andrade Marin HospitalAvenida Ayacucho y 18 de Septiembre QuitoEcuador
                Author notes
                [*] [* ] Correspondence

                Edgar Patricio Correa Díaz, Department of Neurology at Carlos Andrade Marin Hospital, Avenida Ayacucho y 18 de Septiembre, Quito 170411, Ecuador. Tel: +593 99 679 4692; E‐mail: patocorrea2010@ 123456yahoo.com

                Author information
                http://orcid.org/0000-0001-6363-8886
                Article
                CCR3873
                10.1002/ccr3.873
                5378834
                614c15de-6cd4-4771-ac51-c7790e62673b
                © 2017 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.

                This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

                History
                : 31 August 2016
                : 22 January 2017
                : 31 January 2017
                Page count
                Figures: 1, Tables: 0, Pages: 2, Words: 640
                Categories
                Clinical Image
                Clinical Images
                Custom metadata
                2.0
                ccr3873
                April 2017
                Converter:WILEY_ML3GV2_TO_NLMPMC version:5.0.9 mode:remove_FC converted:04.04.2017

                cognitive impairment,epilepsy,neurocysticercosis
                cognitive impairment, epilepsy, neurocysticercosis

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