The concept of the MUSE-Tech project is the integration of three High-End sensing technologies (Photoacoustic Spectroscopy, Quasi Imaging UV-Vis Spectrometry and Distributed Temperature Sensing) in a versatile Multi Sensor Device (MSD), for real-time monitoring (on-line or in-line) of multiple parameters associated with the quality and the chemical safety of raw and in-process materials. The MUSE-Tech project will bridge the gap between state of the art sensing technologies and industrial Process Analytical Technology (PAT) applications by demonstrating fitness for purpose of the versatile Multi Sensor Device (MSD) in three case studies: Bread production (dough mixing and prover fermentation), Potato chips frying and Brewing (wort mashing and boiling).