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      Inulin as a growth promoter in diets for rabbits

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          Abstract

          Sixty New Zealand rabbits aged 40 days were divided into 4 groups of 15 animals. The control group received a free diet of antibiotic growth promoter (AGP) and inulin. The second group was supplemented with 2.5 g/kg of inulin. The third was administered AGP with 0.1 g/kg of flavomycin. Finally, the fourth group received a 2.5 and 0.1 g/kg inulin/AGP diet. Body weight gain was higher in the control group. Rabbits supplemented with inulin had lower values ​​of triglycerides compared with the control and AGP groups, and their glucose level was significantly lower than those treated with AGP. Additionally, serum calcium and magnesium concentrations were higher than the other groups, particularly with regard to AGP. The bone content with regard to calcium, phosphorus and magnesium in the groups treated with inulin was higher compared with the control; moreover, phosphorus and magnesium were higher than in the AGP group. The thickness of the mucosa and crypt depth in the caecum were significantly higher in rabbits treated with inulin than in the other groups, but especially compared with the AGP group. Also, triglyceride values ​​were lower for rabbits treated with inulin/AGP than for those treated with AGP and the bone magnesium concentration was significantly higher compared with the control group. In addition, inulin was shown to have positive effects on the rabbit, promoting increase in bone and serum calcium, magnesium and phosphorus, decrease in triglyceride levels, and improvement in the caecum (changes in morphology, crypt depth and mucosal thickness).

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          Propionate as a health-promoting microbial metabolite in the human gut.

          Propionate is a major microbial fermentation metabolite in the human gut with putative health effects that extend beyond the gut epithelium. Propionate is thought to lower lipogenesis, serum cholesterol levels, and carcinogenesis in other tissues. Steering microbial propionate production through diet could therefore be a potent strategy to increase health effects from microbial carbohydrate fermentation. The present review first discusses the two main propionate-production pathways and provides an extended gene-based list of microorganisms with the potential to produce propionate. Second, it evaluates the promising potential of arabinoxylan, polydextrose, and L-rhamnose to act as substrates to increase microbial propionate. Third, given the complexity of the gut microbiota, propionate production is approached from a microbial-ecological perspective that includes interaction processes such as cross-feeding mechanisms. Finally, it introduces the development of functional gene-based analytical tools to detect and characterize propionate-producing microorganisms in a complex community. The information in this review may be helpful for designing functional food strategies that aim to promote propionate-associated health benefits. © 2011 International Life Sciences Institute.
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            Effects of short chain fatty acids on gut morphology and function.

            Short chain fatty acids (SCFAs) are the products of colonic bacterial degradation of unabsorbed starch and non-starch polysaccharide (fibre). They are important anions in the colonic lumen, affecting both colonocyte morphology and function. The three main acids (acetate, propionate, and butyrate) stimulate colonic sodium and fluid absorption and exert proliferative effects on the colonocyte. Experimental animal studies have shown that they promote adaptive responses to small intestinal resection and colonic anastomosis. Acetate increases colonic blood flow and enhances ileal motility. Butyrate has been shown to be the preferred energy substrate for the colonocyte and to be a potent differentiating agent in cell culture. Butyrate may also have a role in preventing certain types of colitis. A diet low in resistant starch and fibre, which will result in a low production of SCFAs in the colon, may explain the high occurrence of colonic disorders seen in the Western civilization.
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              Efficacy of probiotics from anaerobic microflora with prebiotics on growth performance and noxious gas emission in growing pigs.

              We investigated the effect of probiotics from anaerobic microflora with prebiotics (synbiotics) on growth performance, noxious gas emission and fecal pathogenic bacteria populations in growing pigs. The basal diet, which contained approximately 25% corn, 24% whey, 12% wheat and 12% soybean meal, was supplemented alternatively with 0.15% antibiotics (US diet), prebiotics and 0.2% probiotics from anaerobic bacteria (BS diet), yeast (YS diet), mold (MS diet) or compounds (CS diet). One hundred and fifty pigs were fed an experimental diet for 15 days. Although the growth performance was not affected by supplemental synbiotics, the BS group showed higher dry matter and crude protein digestibility. The BS group decreased fecal ammonia and amine gas emissions, and increased fecal acetate gas emission compared with the US group. All synbiotics groups decreased in fecal propionate gas emission. Fecal Escherichia coli population was lower in the synbiotics groups than in the US group. Therefore, the results of the present study suggest that synbiotics exert similar effects with antibiotics on the nutrient digestibility and fecal microflora composition in growing pigs. Moreover, synbiotics can also decrease the fecal noxious gas emission in growing pigs.
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                Author and article information

                Contributors
                Role: ND
                Role: ND
                Role: ND
                Role: ND
                Role: ND
                Role: ND
                Journal
                rbz
                Revista Brasileira de Zootecnia
                R. Bras. Zootec.
                Sociedade Brasileira de Zootecnia (Viçosa )
                1806-9290
                December 2013
                : 42
                : 12
                : 885-891
                Affiliations
                [1 ] Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán Mexico
                [2 ] Universidad Autónoma Metropolitana Mexico
                Article
                S1516-35982013001200008
                10.1590/S1516-35982013001200008
                642e9797-2b5a-4b77-8e37-4b4a8c3c2a18

                http://creativecommons.org/licenses/by/4.0/

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                SciELO Brazil

                Self URI (journal page): http://www.scielo.br/scielo.php?script=sci_serial&pid=1516-3598&lng=en
                Categories
                AGRICULTURE, DAIRY & ANIMAL SCIENCE
                VETERINARY SCIENCES

                Animal agriculture,General veterinary medicine
                bone,caecal,crypts,diet,inulin,minerals,mucosa
                Animal agriculture, General veterinary medicine
                bone, caecal, crypts, diet, inulin, minerals, mucosa

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