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      Comparison of Systolic Blood Pressure Values Obtained by Photoplethysmography and by Korotkoff Sounds

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          Abstract

          In the current study, a non-invasive technique for systolic blood pressure (SBP) measurement based on the detection of photoplethysmographic (PPG) pulses during pressure-cuff deflation was compared to sphygmomanometry—the Korotkoff sounds technique. The PPG pulses disappear for cuff-pressures above the SBP value and reappear when the cuff-pressure decreases below the SBP value. One hundred and twenty examinations were performed on forty subjects. In 97 examinations the two methods differed by less than 3 mmHg. In nine examinations the SBP value measured by PPG was higher than that measured by sphygmomanometry by 5 mmHg or more. In only one examination the former was lower by 5 mmHg or more than the latter. The appearance of either the PPG pulses or the Korotkoff sounds assures that the artery under the cuff is open during systolic peak pressure. In the nine examinations mentioned above the PPG pulses were observed while Korotkoff sounds were not detected, despite the open artery during systole. In these examinations, the PPG-based technique was more reliable than sphygmomanometry. The high signal-to-noise ratio of measured PPG pulses indicates that automatic measurement of the SBP by means of automatic detection of the PPG signals is feasible.

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          Most cited references33

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          Blood pressure measuring devices: recommendations of the European Society of Hypertension.

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            Arterial blood pressure measurement and pulse wave analysis--their role in enhancing cardiovascular assessment.

            The most common method of clinical measurement of arterial blood pressure is by means of the cuff sphygmomanometer. This instrument has provided fundamental quantitative information on arterial pressure in individual subjects and in populations and facilitated estimation of cardiovascular risk related to levels of blood pressure obtained from the brachial cuff. Although the measurement is taken in a peripheral limb, the values are generally assumed to reflect the pressure throughout the arterial tree in large conduit arteries. Since the arterial pressure pulse becomes modified as it travels away from the heart towards the periphery, this is generally true for mean and diastolic pressure, but not for systolic pressure, and so pulse pressure. The relationship between central and peripheral pulse pressure depends on propagation characteristics of arteries. Hence, while the sphygmomanometer gives values of two single points on the pressure wave (systolic and diastolic pressure), there is additional information that can be obtained from the time-varying pulse waveform that enables an improved quantification of the systolic load on the heart and other central organs. This topical review will assess techniques of pressure measurement that relate to the use of the cuff sphygmomanometer and to the non-invasive registration and analysis of the peripheral and central arterial pressure waveform. Improved assessment of cardiovascular function in relation to treatment and management of high blood pressure will result from future developments in the indirect measurement of arterial blood pressure that involve the conventional cuff sphygmomanometer with the addition of information derived from the peripheral arterial pulse.
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              A mathematical study of some biomechanical factors affecting the oscillometric blood pressure measurement.

              A mathematical lumped parameter model of the oscillometric technique for indirect blood pressure measurement is presented. The model includes cuff compliance, pressure transmission from the cuff to the brachial artery through the soft tissue of the arm, and the biomechanics of the brachial artery both at positive and negative transmural pressure values. The main aspects of oscillometry are simulated i.e., the increase in cuff pressure pulsatility during cuff deflation maneuvers, the existence of a point of maximum pulsations (about 1.5 mmHg) at a cuff pressure close to mean arterial pressure, and the characteristic ratios for cuff pressure pulsatility at systole and diastole (0.52 and 0.70, respectively, with this model, using basal parameters and an individual set of data for the arterial pressure waveform). Subsequently, the model is used to examine how alterations in some biomechanical factors may prejudice the accuracy of pressure measurement. Numerical simulations indicate that alterations in wall viscoelastic properties and in arterial pressure pulse amplitude may significantly affect the accuracy of pressure estimates, leading to errors as great as 15-20% in the computation of diastolic and systolic arterial pressure. By contrast, changes in arterial pressure mean value and cuff compliance do not seem to have significant influence on the measurement. Evaluation of mean arterial pressure through a characteristic ratio is not robust and may lead to misleading results. Mean arterial pressure may be better evaluated as the lowest pressure at which cuff pulse amplitude reaches a plateau. The obtained results may help to explain the nature of errors which usually limit the reliability of arterial pressure measurement (for instance in the elderly).
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                Author and article information

                Journal
                Sensors (Basel)
                Sensors (Basel)
                Sensors (Basel, Switzerland)
                Molecular Diversity Preservation International (MDPI)
                1424-8220
                November 2013
                31 October 2013
                : 13
                : 11
                : 14797-14812
                Affiliations
                [1 ] Department of Physics/Electro-Optics, Jerusalem College of Technology, Jerusalem 9116001, Israel; E-Mails: yadar@ 123456g.jct.ac.il (Y.A.); hoffman18@ 123456gmail.com (E.H.); eransh@ 123456g.jct.ac.il (E.S.)
                [2 ] Department of Electronics, Jerusalem College of Technology, Jerusalem 9116001, Israel; E-Mail: shlomoe@ 123456jct.ac.il
                [3 ] Nephrology and Hypertension Services, Hadassah-Hebrew University Medical Center, Jerusalem 9112000, Israel; E-Mail: iddo@ 123456hadassah.org.il
                [4 ] Department of Internal Medicine, Hadassah-Hebrew University Medical Center, Jerusalem 9124000, Israel; E-Mail: bursz@ 123456mail.huji.ac.il
                Author notes
                [* ] Author to whom correspondence should be addressed; E-Mail: nitzan@ 123456jct.ac.il ; Tel.: +972-2-675-1139; Fax: +972-2-675-1045.
                Article
                sensors-13-14797
                10.3390/s131114797
                3871084
                24184918
                65ab5e67-d15b-43d3-9ce3-58d9b954e23d
                © 2013 by the authors; licensee MDPI, Basel, Switzerland.

                This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license ( http://creativecommons.org/licenses/by/3.0/).

                History
                : 02 September 2013
                : 08 October 2013
                : 25 October 2013
                Categories
                Article

                Biomedical engineering
                systolic blood pressure,sphygmomanometry,korotkoff sounds,photoplethysmography,accuracy

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