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      Autologous Serum Tears for Treatment of Photoallodynia in Patients with Corneal Neuropathy: Efficacy and Evaluation with In Vivo Confocal Microscopy.

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          Abstract

          Patients suffering from corneal neuropathy may present with photoallodynia; i.e., increased light sensitivity, frequently with a normal slit-lamp examination. This study aimed to evaluate the efficacy of autologous serum tears (AST) for treatment of severe photoallodynia in corneal neuropathy and to correlate clinical findings with corneal subbasal nerve alterations by in vivo confocal microscopy (IVCM).

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          Author and article information

          Journal
          Ocul Surf
          The ocular surface
          1937-5913
          1542-0124
          Jul 2015
          : 13
          : 3
          Affiliations
          [1 ] Ocular Surface Imaging Center, Cornea and Refractive Surgery Service, Massachusetts Eye & Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
          [2 ] Pain/Analgesia Imaging Neuroscience (P.A.I.N.) Group, Department of Anesthesia, Boston Children's Hospital, Center for Pain and the Brain, Harvard Medical School, Waltham, MA, USA.
          [3 ] Department of Neurology, Charité University Medicine Berlin, Germany.
          [4 ] Ocular Surface Imaging Center, Cornea and Refractive Surgery Service, Massachusetts Eye & Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA. Electronic address: pedram_hamrah@meei.harvard.edu.
          Article
          S1542-0124(15)00009-9 NIHMS671717
          10.1016/j.jtos.2015.01.005
          4499014
          26045233
          66073b52-0346-4ede-841f-5df1007105a4
          Copyright © 2015 Elsevier Inc. All rights reserved.
          History

          autologous serum tears,corneal neuropathy,laser in vivo confocal microscopy,light sensitivity,nerve growth factor,photoallodynia,regeneration

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