CHEMICAL CONSTITUENTS AND PHARMACOLOGICAL EFFECTS OF HYPERICUM TRIQUETRIFOLIUM

Abstract

Hypericum triquetrifolium contained many biologically active chemicals included acylphloroglucinols triquetrireboudin, triquetriborin, essential and volatile oils and many phenolic compounds. Hypericum triquetrifolium contained hyperforin 0.013 ± 0.000 and hypericin 0.020 ± 0.001 w/w%. Many phenolics were isolated from Hypericum triquetrifolium included chlorogenic acid, caffeoylquinic acid, p-coumaroylquinic acid, epicatechin, rutin, hyperoside, I3,II8-biapigenin, isoquercetine, quercitrine, quercetine, quercetin galactoside, quercetin rutinoside, quercetin-3-O-galactoside, kaempferol-3-O-glycoside, apigenin-7-O-glucoside, kaempferol and amentoflavone. The pharmacological studies showed that Hypericum triquetrifolium possessed antinflammatory, analgesic, antioxidant, cytotoxic, antimicrobial and vasorelaxant effects. This review will highlight the chemical constituents and pharmacological effects of Hypericum triquetrifolium. Keywords: Chemical constituents, pharmacology, Hypericum triquetrifolium