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      Seminal vesicle sparing laparoscopic radical prostatectomy using a low-energy source: Better continence and potency

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          Abstract

          Objectives:

          Ongoing with the newer developments in laparoscopic radical prostatectomy (LRP), we report our experience in a consecutive series of 42 patients with a mean 18-month follow-up. We also studied the use of a low-energy source, especially in the region of the prostatic apex and the neurovascular bundle and evaluated its outcome on continence and potency.

          Materials and Methods:

          Between November 2003 and December 2008, 50 patients aged 50–80 yrs underwent LRP with vesicourethral anastomosis and of these, 42 patients who had a minimum follow-up of 3 months were selected for the study. Of these, the initial 16 patients were operated by the routine method and the 26 patients operated in the later part of our experience were operated upon using a minimal energy source.

          Results:

          The mean follow-up was 18 months (range 3–60). Continence was evaluated at 1, 3, 6, and 12 months. Eleven of the 16 patients in Group I were continent as compared with 21 of 26 patients in Group II. The difference in continence rates was mainly due to less use of electrocautery and harmonic scalpel at the bladder neck. Of the eight patients who were potent pre-operatively in Group I, four remained potent 3 months after LRP. In Group II, 20 of the 26 patients were potent pre-operatively and 16 remained potent 3 months after LRP.

          Conclusions:

          Use of a low-energy source at the bladder neck and neurovascular bundle, sparing of seminal vesicle, and leaving behind a long, healthy stump of the urethra during apical dissection, is associated with better continence and potency without compromising oncological outcome.

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          Most cited references20

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          Anatomic radical prostatectomy: evolution of the surgical technique.

          P C Walsh (1998)
          Although radical prostatectomy provided excellent cancer control, it never gained widespread popularity because of the major side effects of incontinence, impotence and excessive blood loss. The reason for this morbidity was a deficit in the understanding of the periprostatic anatomy. The evolution of the surgical technique for anatomic radical prostatectomy is described. Beginning in 1974 anatomic observations in the operating room were used to clarify the anatomy of the dorsal vein complex, pelvic plexus, striated urethral sphincter and lateral pelvic fascia. These intraoperative observations were amplified using dissections in stillborns and step section whole mount adult cadaveric studies. Armed with improved information about the periprostatic anatomy, an anatomical approach to radical prostatectomy was developed. This surgical technique has improved surgical exposure, lowered blood loss, reduced urinary incontinence, made it possible to preserve potency and provided excellent cancer control. With the reduction in morbidity, radical prostatectomy today is an ideal treatment for the cure of prostate cancer in a patient who is curable and who is going to live long enough to need to be cured. Also the widespread application of radical prostatectomy has provided tissue and valuable pathological information that has galvanized research in the field.
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            Laparoscopic and robot assisted radical prostatectomy: establishment of a structured program and preliminary analysis of outcomes.

            The technique of laparoscopic radical prostatectomy is difficult to master and is associated with a steep learning curve. We hypothesized that a structured approach to establishing a laparoscopic prostatectomy program would diminish complications during the learning process and that robotic technology would be useful in learning the operation. A structured laparoscopic radical prostatectomy program was introduced at the Vattikuti Urology Institute on October 23, 2000. One of 2 surgeons with a combined experience of more than 500 laparoscopic radical prostatectomies performed or supervised the first prostatectomies, training a third surgeon with extensive "open" surgical skills but no laparoscopic experience. The "trained" surgeon then started performing the operation independently with robotic assistance. The results of this approach were analyzed at the end of 12 months. We performed 48 laparoscopic radical prostatectomies and 50 robot assisted prostatectomies within the 12-month period. The preoperative and intraoperative demographical variables were comparable in both groups as were the operative times, changes in hemoglobin concentrations, durations of hospitalization, positive margin rates and overall complication rates. All measured parameters were comparable to the "best-in-class" values for laparoscopic radical prostatectomy reported in the literature. A structured approach minimizes complications during the establishment of laparoscopic radical prostatectomy program. Robotic assistance helps skilled "open" surgeons learn the technique of laparoscopic radical prostatectomy.
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              Laparoscopic radical prostatectomy: the Montsouris experience.

              We evaluate our experience with laparoscopic radical prostatectomy. Between February 1, 1998 and May 1, 1999, 120 consecutive patients underwent laparoscopic radical prostatectomy. Morbidity of the first 40 (group 1), next 40 (group 2) and last 40 (group 3) procedures was compared. Oncological data were assessed by pathological examination and postoperative prostate specific antigen (PSA). Functional results were assessed by a self-administered questionnaire for the first 60 patients and potency was assessed in the last 40. Mean operating time plus or minus standard deviation was 239+/-59 minutes (range 150 to 450) for the series, and 282, 247 and 231, respectively, for groups 1, 2 and 3. Surgical conversion was necessary in 7 cases (5.8%) overall, including 10% (4) in group 1, 7.5% (3) in group 2 and 0% in group 3. Mean intraoperative bleeding was 402+/-293 ml. (range 50 to 1,500) in the series, and 534, 517 and 277, respectively, for groups 1, 2 and 3. The transfusion rate was 10% overall, and 15%, 12.5% and 2.5%, respectively, in groups 1, 2 and 3. The reoperation rate was 1.7%. Mean postoperative bladder catheterization time was 6.6+/-2.4 days. The positive and questionable surgical margin rate was 15%. Pathological tumor stage was pT2a in 4 specimens (11%), pT2b in 11 (16%), pT3a in 0 and pT3b in 3 (50%) with positive surgical margins. PSA assays were available in 94 patients with a mean postoperative followup of 2.2 months (range 1 to 12). Serum PSA was 0.1 ng./ml. or less in 89 men (94.7%). The continence rate at 6 months postoperatively was 72% among the first 60 patients. Of 20 group 3 patients who were sexually active preoperatively 9 (45%) reported postoperative spontaneous erections. The overall cost of retropubic radical prostatectomy was about $1,237 more than that for laparoscopy. Laparoscopic radical prostatectomy is feasible and perioperative morbidity is low. Based on our postoperative followup, oncological results are identical to those of conventional surgery and functional results are encouraging.
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                Author and article information

                Journal
                Indian J Urol
                IJU
                Indian Journal of Urology : IJU : Journal of the Urological Society of India
                Medknow Publications (India )
                0970-1591
                1998-3824
                Apr-Jun 2009
                : 25
                : 2
                : 199-202
                Affiliations
                Department of Urology, Civil Hospital, B.J. Medical College and Civil Hospital, Asarwa, Ahmedabad, India
                Author notes
                For correspondence: Dr. Shrenik J. Shah, Department of Urology, A-1 Ward, Civil Hospital, B.J. Medical College and Civil Hospital, Asarwa, Ahmedabad, India. E-mail: urologycha@ 123456gmail.com
                Article
                IJU-25-199
                10.4103/0970-1591.52913
                2710064
                19672346
                68881bc7-671e-46cb-be14-e39786fe3a69
                © Indian Journal of Urology

                This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                Categories
                Original Article

                Urology
                prostatectomy,radical,prostate
                Urology
                prostatectomy, radical, prostate

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