Imbalance of morphofunctional responses of Jurkat T lymphoblasts at short-term culturing with relief zinc- or copper-containing calcium phosphate coating on titanium.

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Abstract

Morphofunctional response of Jurkat T cells that were cultured for 24 h on substrates prepared from commercially pure titanium with relief microarc bilateral calcium phosphate coating containing copper or zinc was studied. Changes in the concentration of essential trace elements contained in this coating can cause significant imbalance of molecular processes of differentiation, secretion, apoptosis, and necrosis and reduce tumor cell survival.

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Journal

Journal ID (iso-abbrev): Dokl Biochem Biophys

Title: Doklady. Biochemistry and biophysics

Publisher: Pleiades Publishing Ltd

ISSN (Electronic): 1608-3091

ISSN (Print): 1607-6729

Publication date (Electronic): Jan 2017

Volume: 472

Issue: 1

Affiliations

[1 ] Immanuel Kant Baltic Federal University, Kaliningrad, 236041, Russia. larisalitvinova@yandex.ru.

[2 ] Immanuel Kant Baltic Federal University, Kaliningrad, 236041, Russia.

[3 ] Siberian State Medical University, Ministry of Healthcare of the Russian Federation, Tomsk, 634050, Russia.

[4 ] Tomsk Polytechnic University, Tomsk, 634050, Russia.

[5 ] Institute of Strength Physics and Materials Science, Siberian Branch, Russian Academy of Sciences, Tomsk, 634055, Russia.

Article

Publisher Item ID: 10.1134/S1607672917010094

DOI: 10.1134/S1607672917010094

PubMed ID: 28421430

SO-VID: 6dad7d8e-2f89-49b1-a6a1-b4239daa6bb5

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