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      Effect of three fodder trees on Haemonchus contortus control and weight variations in kids Translated title: Efecto de tres árboles forrajeros en el control de Haemonchus contortus y cambios de peso en cabritos

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          Abstract

          The objective was to evaluate the activity against Haemonchus contortus by foliage taken from three tanniferous tree species and fed to Creole male kids experimentally infected with a dose of 350 larvae of H. contortus (L3) kg-1 body weight (BW). Twenty Creole kids weighing 12 ± 2.0 kg were randomly distributed in four treatments: T1 = control without foliage, and the addition of fresh foliage (10 % of the dry matter of the total diet) of Guazuma ulmifolia (T2), Pithecellobium dulce (T3) and Acacia cochliacantha (T4). For sixty days, the activity of the foliage against H. contortus was evaluated by quantifying the reduction in the excretion of eggs per gram of feces; also, the excretion of eggs was associated with the concentration of the blood cell pack, dry matter intake and weight change in animals. The data of the evaluated variables were analyzed in a completely randomized design and a Tukey test was carried out for comparison of means (p < 0.05). The secondary compounds of P. dulce and A. cochliacanta foliage were more effective (p < 0.04) in the control of H. contortus with minor excretion of eggs (1.48 and 1.18 Log10 g-1 of feces), respectively. The hematocrit was different (p < 0.005) mainly in hemoglobin, erythrocytes, lymphocytes and eosinophils; dry matter intake (p < 0.05) and changes in total body weight (p < 0.01) were higher in kids which received P. dulce foliage (T3) with 621.5 g d-1 and 2.4 kg, respectively. It was concluded that the secondary compounds of fresh P. dulce and A. cochliacantha foliage have the potential to control H. contortus without affecting the health and productive response in kids.

          Translated abstract

          El objetivo fue evaluar la actividad contra Haemonchus contortus del follaje de tres árboles taniníferos en cabritos criollos infestados experimentalmente con una dosis de 350 larvas de H. contortus (L3) Kg-1 peso vivo. Veinte cabritos criollos de 12 ± 2.0 kg de peso vivo (PV), fueron distribuidos al azar en cuatro tratamientos: Tl= testigos sin follaje, y la adición de follaje fresco (10 % de la materia seca de la dieta total) de Guazuma ulmifolia (T2), Phitecellobium dulce (T3) y Acacia cochliacantha (T4). Durante 60 d se evaluó la actividad de los follajes contra H. contortus mediante la reducción en la excreción de huevos por gramo de heces (hpgh); además, la excreción de huevecillos se asoció con la concentración del paquete celular sanguíneo y el cambio de peso de los animales. Los datos de las variables evaluadas se analizaron en un diseño completamente al azar y la prueba de Tukey para la comparación de medias (p < 0.05). Los compuestos secundarios del follaje de P. dulce y A. cochliacanta resultaron más eficaces (p < 0.04) en el control de H. contortus, con menor excreción de hpgh (1.48 y 1.18 Log10 g-1 de heces), respectivamente. El hematocrito fue diferente (p < 0.005) principalmente en hemoglobina, eritrocitos, linfocitos y eosinófilos; el consumo de materia seca (p < 0.05) y el cambio de peso vivo total (p < 0.01) fue mayor en los cabritos que recibieron el follaje de P. dulce con 621.5 g d-1 y 2.4 kg de peso, respectivamente. Se concluye que los follajes de P. dulce y A. cochliacanta, por su contenido de taninos, tienen potencial para el control de H. contortus, lo que amerita mayor investigación.

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          The genome and developmental transcriptome of the strongylid nematode Haemonchus contortus

          Background The barber's pole worm, Haemonchus contortus, is one of the most economically important parasites of small ruminants worldwide. Although this parasite can be controlled using anthelmintic drugs, resistance against most drugs in common use has become a widespread problem. We provide a draft of the genome and the transcriptomes of all key developmental stages of H. contortus to support biological and biotechnological research areas of this and related parasites. Results The draft genome of H. contortus is 320 Mb in size and encodes 23,610 protein-coding genes. On a fundamental level, we elucidate transcriptional alterations taking place throughout the life cycle, characterize the parasite's gene silencing machinery, and explore molecules involved in development, reproduction, host-parasite interactions, immunity, and disease. The secretome of H. contortus is particularly rich in peptidases linked to blood-feeding activity and interactions with host tissues, and a diverse array of molecules is involved in complex immune responses. On an applied level, we predict drug targets and identify vaccine molecules. Conclusions The draft genome and developmental transcriptome of H. contortus provide a major resource to the scientific community for a wide range of genomic, genetic, proteomic, metabolomic, evolutionary, biological, ecological, and epidemiological investigations, and a solid foundation for biotechnological outcomes, including new anthelmintics, vaccines and diagnostic tests. This first draft genome of any strongylid nematode paves the way for a rapid acceleration in our understanding of a wide range of socioeconomically important parasites of one of the largest nematode orders.
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            Beneficial and detrimental effects of dietary condensed tannins for sustainable sheep and goat production—Progress and challenges

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              Plant extracts to manipulate rumen fermentation

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                Author and article information

                Journal
                era
                Ecosistemas y recursos agropecuarios
                Ecosistemas y recur. agropecuarios
                Universidad Juárez Autónoma de Tabasco, Dirección de Investigación y Posgrado (Villahermosa, Tabasco, Mexico )
                2007-9028
                2007-901X
                August 2015
                : 2
                : 5
                : 193-201
                Affiliations
                [04] Iguala Guerrero orgnameInstituto Nacional de Investigaciones Forestales Agrícolas y Pecuarias México
                [03] Xochimilco Distrito Federal orgnameUniversidad Autónoma Metropolitana orgdiv1Departamento de Producción Agrícola y Animal México
                [02] Puebla orgnameBenemérita Universidad Autónoma de Puebla orgdiv1Facultad de Medicina Veterinaria y Zootecnia orgdiv2Laboratorio de Genética y Reproducción México
                [01] Chilpancingo Guerrero orgnameUniversidad Autónoma de Guerrero orgdiv1Unidad Académica de Medicina Veterinaria y Zootecnia México olivaares@ 123456hotmail.com
                Article
                S2007-90282015000200007 S2007-9028(15)00200500007
                7097510d-f558-4032-8830-3e7be3e3b4c1

                This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

                History
                : 06 October 2014
                : 27 July 2014
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 38, Pages: 9
                Product

                SciELO Mexico

                Categories
                Scientific articles

                H. contortus,Guazuma ulmifolia,Phitecellobium dulce,Acacia cochliacantha

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