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      Estudo por imagem da artrite reumatóide no quadril Translated title: Hip imaging in rheumatoid arthritis

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          Abstract

          Este artigo de revisão tem como objetivo discutir os principais aspectos por imagem do envolvimento do quadril em adultos pela artrite reumatóide, com abordagem ilustrativa dos principais achados. Os métodos de imagem estudados são a radiografia, ultra-sonografia, tomografia computadorizada e a ressonância magnética com o uso do contraste paramagnético (gadolínio) pela via intravenosa.

          Translated abstract

          The aim of this article is to discuss the main aspects of the hip involvement in adults with rheumatoid arthritis. The diagnostic imaging methods that will be illustrated are radiography, ultrasonography, computer tomography and magnetic resonance imaging (MRI) with gadolinium endovenous injection.

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          Most cited references103

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          Rheumatoid arthritis. Pathophysiology and implications for therapy.

          E D Harris (1990)
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            Radiographic evaluation of rheumatoid arthritis and related conditions by standard reference films.

            A review of radiographic evaluation of rheumatoid arthritis is given. Standard reference films are introduced for evaluation of rheumatoid arthritis and related conditions in the extremity joints. In this system, numerical evaluation of arthritis is given for individual joints in a patient.
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              Bone edema scored on magnetic resonance imaging scans of the dominant carpus at presentation predicts radiographic joint damage of the hands and feet six years later in patients with rheumatoid arthritis.

              Magnetic resonance imaging (MRI) is capable of revealing synovitis and tendinitis in early rheumatoid arthritis (RA), as well as bone edema and erosion. These features are visible before radiographic joint damage occurs. We sought to examine whether MRI of one body region (the wrist) can be used to predict whole-body radiography scores reflecting joint damage at 6 years. We conducted a 6-year prospective study of a cohort of patients who fulfilled the criteria for RA at presentation, using clinical parameters, radiographs, and MRI scans of the dominant wrist. Of the 42 patients enrolled at baseline, full MRI, radiographic, and clinical data were available for 31 at 6-year followup. MRI scans were scored by 2 radiologists, using a validated scoring system. Radiographs of the hands and feet were graded using the modified Sharp scoring method. MRI and radiography scores obtained at baseline and 6 years were compared, and baseline MRI scores were examined for their ability to predict radiographic outcome at 6 years. At 6 years, the total Sharp score correlated significantly with the total MRI score and the MRI erosion score (r = 0.81, P < 0.0001 and r = 0.79, P < 0.0001, respectively). The 6-year Sharp score also correlated with the baseline total MRI and MRI erosion scores (r = 0.56, P < 0.0001 and r = 0.33, P = 0.03, respectively). MRI synovitis and bone edema scores remained constant for the group as a whole over 6 years, but bone erosion scores progressed (P = 0.0001), consistent with radiographic deterioration. Erosions on 6-year MRI scans were frequently preceded by MRI bone edema at baseline (odds ratio 6.5, 95% confidence interval 2.78-18.1). Regression models indicated that the baseline MRI bone edema score was predictive of the 6-year total Sharp score (P = 0.01), as was the C-reactive protein (CRP) level (P = 0.0002). Neither shared epitope status nor swollen or tender joint counts predicted radiographic outcome in this cohort. A model incorporating baseline MRI scores for erosion, bone edema, synovitis, and tendinitis plus the CRP level and the erythrocyte sedimentation rate explained 59% of the variance in the 6-year total Sharp score (R(2) = 0.59, adjusted R(2) = 0.44). MRI scans performed at the first presentation of RA can be used to help predict future radiographic damage, allowing disease-modifying therapy to be targeted to patients with aggressive disease.
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                Author and article information

                Contributors
                Role: ND
                Role: ND
                Role: ND
                Journal
                rbr
                Revista Brasileira de Reumatologia
                Rev. Bras. Reumatol.
                Sociedade Brasileira de Reumatologia (São Paulo, SP, Brazil )
                0482-5004
                1809-4570
                August 2005
                : 45
                : 4
                : 206-214
                Affiliations
                [01] orgnameUnifesp orgdiv1EPM orgdiv2Departamento de Diagnóstico por Imagem
                [02] orgnameUnifesp orgdiv1EPM orgdiv2Disciplina de Reumatologia
                Article
                S0482-50042005000400004
                10.1590/S0482-50042005000400004
                7239c58a-b2d2-49bd-b762-37e1f498ba94

                This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

                History
                : 09 February 2005
                : 22 July 2004
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 70, Pages: 9
                Product

                SciELO Brazil

                Categories
                Artigos de Revisão

                artrite reumatóide,quadril,imagem,ressonância magnética,gadolínio,rheumatoid arthritis,hip,imaging,magnetic resonance imaging,gadolinium

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