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      Relación entre la medición sonográfica de los músculos recto femoral y vasto intermedio y los parámetros bioquímicos convencionales para valorar el estado nutricional en la unidad de cuidados intensivos Translated title: Relação entre a medida ultrassonográfica dos músculos reto femoral e vasto intermédio com parâmetros bioquímicos convencionais para avaliação do estado nutricional na Unidade de Terapia Intensiva Translated title: Relationship between the sonographic measurement of the rectus femoris and vastus intermedius muscles and the conventional biochemical parameters used to assess the nutritional status in the intensive care unit

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          Abstract

          Resumen: Introducción: La desnutrición en el paciente crítico se relaciona con mal pronóstico. Las pérdidas proteicas se identifican de manera convencional mediante parámetros bioquímicos. La masa muscular puede reflejar la reserva corporal de proteínas, su medición por medio de sonografía ha evidenciado una fuerte correlación para detección de alteraciones. Objetivo: Determinar la correlación de la medición sonográfica de los músculos Recto Femoral (RF) y Vasto Intermedio (VI), con los parámetros bioquímicos convencionales de valoración nutricional. Métodos: Se estudiaron 12 pacientes mayores de 18 años, que recibieron dieta enteral temprana. Se midieron los parámetros bioquímicos, simultáneamente con parámetros sonográficos a nivel de RF y VI en los días uno y siete. Se estableció correlación entre los parámetros bioquímicos y sonográficos significativos. Resultados: El parámetro bioquímico con mayor significancia estadística fue el Balance Nitrogenado Urinario (BNU) en muestra de orina de 24 horas (p=0.001). En mediciones sonográficas, el porcentaje de reducción muscular para RF y VI mostró mayor diferencia (p=0.001). En análisis de correlación, se obtuvo fuerte correlación entre BNU y RF (r=0.77) así como BNU y VI (r=0.76). Conclusión: Existe correlación entre las pérdidas proteicas medidas por BNU y el porcentaje de reducción de los músculos RF y VI medidos por sonografía.

          Translated abstract

          Resumo: Introdução: A desnutrição em pacientes críticos está associada a um mau prognóstico. As perdas de proteína são identificadas convencionalmente por parâmetros bioquímicos. A massa muscular pode refletir a reserva protéica corporal, sua medida por meio da ultrassonografia tem mostrado uma forte correlação para a detecção de alterações. Objetivo: Determinar a correlação da medida ultrassonográfica dos músculos Reto Femoral (RF) e Vasto Intermediário (VI), com os parâmetros bioquímicos convencionais de avaliação nutricional. Métodos: Foram estudados 12 pacientes com mais de 18 anos que receberam dieta enteral precocemente. Os parâmetros bioquímicos foram mensurados simultaneamente com parâmetros ultrassonográficos ao nível de FR e VI nos dias um e sete. Foi estabelecida correlação entre os parâmetros bioquímicos e ultrassonográficos significativos. Resultados: O parâmetro bioquímico com maior significância estatística foi o Balanço de Nitrogênio Urinário (NBU) em uma amostra de urina de 24 horas (p = 0,001). Nas medidas ultrassonográficas, a porcentagem de redução muscular para FR e VI mostrou maior diferença (p = 0,001). Na análise de correlação, obteve-se forte correlação entre o BNU e FR (r = 0,77) e NBU e VI (r = 0,76). Conclusão: Existe uma correlação entre as perdas protéicas medidas pelo NBU e a redução percentual dos músculos RF e VI medida pela ultra-sonografia.

          Translated abstract

          Abstract: Introduction: Malnutrition in critically ill patients is associated with poor prognosis. Protein losses are identified conventionally by biochemical parameters. The muscle mass can reflect the body protein reserve, its measurement by means of sonography has shown a strong correlation for the detection of alterations. Objective: To determine the correlation of the sonographic measurement of the Rectus Femoris (RF) and Vastus Intermedius (VI) muscles, with the conventional biochemical parameters of nutritional assessment. Methods: We studied 12 patients older than 18 years who received an early enteral diet. The biochemical parameters were measured, simultaneously with sonographic parameters at the level of RF and VI on days one and seven. Correlation was established between the significant biochemical and sonographic parameters. Results: The biochemical parameter with the greatest statistical significance was the Urinary Nitrogen Balance (UNB) in a 24-hour urine sample (p = 0.001). In sonographic measurements, the percentage of muscle reduction for RF and VI showed greater difference (p = 0.001). In correlation analysis, strong correlation was obtained between UNB and RF (r = 0.77) as UNB and VI (r = 0.76). Conclusion: There is a correlation between the protein losses measured by UNB and the percentage reduction of RF and VI muscles measured by sonography.

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          Most cited references26

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          Guidelines for the Provision and Assessment of Nutrition Support Therapy in the Adult Critically Ill Patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.).

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            Identifying critically ill patients who benefit the most from nutrition therapy: the development and initial validation of a novel risk assessment tool

            Introduction To develop a scoring method for quantifying nutrition risk in the intensive care unit (ICU). Methods A prospective, observational study of patients expected to stay > 24 hours. We collected data for key variables considered for inclusion in the score which included: age, baseline APACHE II, baseline SOFA score, number of comorbidities, days from hospital admission to ICU admission, Body Mass Index (BMI) < 20, estimated % oral intake in the week prior, weight loss in the last 3 months and serum interleukin-6 (IL-6), procalcitonin (PCT), and C-reactive protein (CRP) levels. Approximate quintiles of each variable were assigned points based on the strength of their association with 28 day mortality. Results A total of 597 patients were enrolled in this study. Based on the statistical significance in the multivariable model, the final score used all candidate variables except BMI, CRP, PCT, estimated percentage oral intake and weight loss. As the score increased, so did mortality rate and duration of mechanical ventilation. Logistic regression demonstrated that nutritional adequacy modifies the association between the score and 28 day mortality (p = 0.01). Conclusions This scoring algorithm may be helpful in identifying critically ill patients most likely to benefit from aggressive nutrition therapy.
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              Skeletal muscle ultrasound: correlation between fibrous tissue and echo intensity.

              In this study, we examined the correlation between muscle ultrasound and muscle structure. Echo intensity (EI) of 14 muscles of two golden retriever muscular dystrophy dogs was correlated to the percentage interstitial fibrous tissue and fat in muscle biopsy. A significant correlation between interstitial fibrous tissue and EI was found (r = 0.87; p < 0.001). The separate influence of interstitial fat on muscle EI could not be established as only little fat was present. We conclude that fibrous tissue causes increased muscle EI. The high correlation between interstitial fibrous tissue and EI makes ultrasound a reliable method to determine severity of structural muscle changes.
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                Author and article information

                Journal
                mccmmc
                Medicina crítica (Colegio Mexicano de Medicina Crítica)
                Med. crít. (Col. Mex. Med. Crít.)
                Colegio Mexicano de Medicina Crítica, A.C. (Ciudad de México, Ciudad de México, Mexico )
                2448-8909
                December 2018
                : 32
                : 6
                : 351-358
                Affiliations
                [1] León orgnameInstituto Mexicano del Seguro Social orgdiv1Centro Médico Nacional Bajío Núm. 1 orgdiv2Unidad Médica de Alta Especialidad Mexico
                Article
                S2448-89092018000600351 S2448-8909(18)03200600351
                737aeab5-b424-40d4-9a8e-7a94af606e6a

                This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

                History
                : 17 November 2018
                : 30 August 2018
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 28, Pages: 8
                Product

                SciELO Mexico

                Categories
                Temas de investigación

                biochemical parameters of nutritional assessment,parámetros bioquímicos de valoración nutricional,Sonografía muscular,Muscle Sonography,parâmetros bioquímicos das avaliação nutricional,Sonografia muscular

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