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      • Record: found
      • Abstract: found
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      Epithelioma Adenoides Cysticum: A Report of Two Cases in a Family

      case-report

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          Abstract

          Epithelioma adenoides cysticum or multiple trichoepitheliomas are rare benign hamartomas arising from the hair germ. A 35-year-old female presented with multiple skin-colored firm papules and nodules mainly affecting the central face, scalp, and external ear canal since the age of 9 years. The lesions gradually increased with age. Her 13-year-old son also had similar but smaller lesions on the central face. Histopathology was consistent with trichoepithelioma.

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          The gene for multiple familial trichoepithelioma maps to chromosome 9p21.

          K Hashimoto, Paulo H. N. Harada, M Ko (1996)
          Multiple familial trichoepithelioma (MFT) is an autosomal dominant skin disease characterized by the presence of many small tumors predominantly on the face. To map the causative gene, we performed linkage analysis with microsatellite markers in three American families. We found a significant linkage of a gene for MFT to chromosome 9p2l. The maximum combined lod score was 3.31 at D9S171 at theta = 0. The disease locus was defined to a 4-cM region between IFNA and D9S126. Because several tumor suppressor genes including p16 and p15 have been mapped to this region, the gene for MFT may also be a tumor suppressor.
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            Giant solitary trichoepithelioma.

            Clarissa Matos, Nivaldo H Toppa, Kathryn da Silva … (1984)
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              Epithelioma adenoides cysticum and solitary trichoepithelioma.

              R. Gray, E B HELWIG (1962)
              Article 0 comments Cited 5 times – based on 0 reviews     Review now
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                Author and article information

                Journal
                Journal ID (nlm-ta): Int J Trichology
                Journal ID (iso-abbrev): Int J Trichology
                Journal ID (publisher-id): IJT
                Title: International Journal of Trichology
                Publisher: Medknow Publications & Media Pvt Ltd (India )
                ISSN (Print): 0974-7753
                ISSN (Electronic): 0974-9241
                Publication date (Print): Oct-Dec 2016
                Volume: 8
                Issue: 4
                Pages: 165-167
                Affiliations
                [1]Department of Dermatology, Medical College, Calicut, Kerala, India
                [1 ]Department of Dermatology, Palakkad Medical College, Palakkad, Kerala, India
                [2 ]Department of Pediatrics, Medical College, Calicut, Kerala, India
                Author notes
                Address for correspondence: Dr. Bindurani Sudhamani, Vrindhavan House, Near Nehru Auditorium, Chittur PO, Palakkad, Kerala, India. E-mail: drbindurani@ 123456gmail.com
                Article
                Publisher ID: IJT-8-165
                DOI: 10.4103/0974-7753.203177
                PMC ID: 5387875
                SO-VID: 75e9bfde-d5d4-4621-95cb-35c19efe21af
                Copyright © Copyright: © 2017 International Journal of Trichology
                License:

                This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

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                Categories
                Subject: Case Report

                ScienceOpen disciplines: Dermatology
                Keywords: brooke's tumor,epithelioma adenoides cysticum,trichoepithelioma
                Data availability:
                ScienceOpen disciplines: Dermatology
                Keywords: brooke's tumor, epithelioma adenoides cysticum, trichoepithelioma

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