For Publishers
DiscoveryMetadataPeer reviewHostingPublishing
For Researchers
JoinPublishReviewCollect
Register
Blog
About
Search
Advanced search
My ScienceOpen
Search
For Publishers
For Researchers
Blog
About
1
views
16
references
 Top references
cited by
0
    
0 reviews
 Review
0
comments
 Comment
0
recommends
+1 Recommend
0 collections
    0
    shares
      174
      similar
       All similar
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Hepatobiliary Brucellosis: Brucella Bacteremia Presenting with Refractory Hepatobiliary Infection

      case-report
      Author(s): 1 , , 1 , , 2
      Publication date (Electronic):
      Journal: Case Reports in Critical Care
      Publisher: Hindawi

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Brucellosis often presents with common and nonspecific symptoms such as fever, malaise, and arthralgia but can also involve primary organs. Intra-abdominal involvement is rare. We report a case of hepatobiliary brucellosis presenting as a refractory hepatobiliary infection in a healthy young adult with no underlying rheumatologic disease or history of exposure to risk factors. Detection of Brucella in the blood led to a shift in the patient's management and consequently her recovery.

          Related collections

          Most cited references16

          • Record: found
          • Abstract: found
          • Article: not found

          Human brucellosis.

          Maria Franco, Maximilian Mulder, Robert Gilman … (2007)
          Human brucellosis still presents scientists and clinicians with several challenges, such as the understanding of pathogenic mechanisms of Brucella spp, the identification of markers for disease severity, progression, and treatment response, and the development of improved treatment regimens. Molecular studies have shed new light on the pathogenesis of Brucella spp, and new technologies have permitted the development of diagnostic tools that will be useful in developing countries, where brucellosis is still a very common but often neglected disease. However, further studies are needed to establish optimum treatment regimens and local and international control programmes. This Review summarises current knowledge of the pathogenic mechanisms, new diagnostic advances, therapeutic options, and the situation of developing countries in regard to human brucellosis.
          Article 0 comments Cited 329 times – based on 0 reviews     Review now
            Bookmark
            • Record: found
            • Abstract: not found
            • Article: not found

            Brucellosis.

            Georgios Pappas, Nikolaos Akritidis, Mile Bosilkovski … (2005)
            Article 0 comments Cited 115 times – based on 0 reviews     Review now
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Complications associated with Brucella melitensis infection: a study of 530 cases.

              Rosa M. Reguera, J Colmenero, F Martos … (1996)
              We carried out a prospective study of 530 patients older than 14 years of age with brucellosis. We describe the incidence and clinical features of the focal forms of the disease, analyzing some of the possible factors associated with their appearance. One hundred sixty-nine patients (31.9%) had a focal form or complication. Osteoarticular complications were the most frequent, totaling 113 cases (66%), followed by genitourinary with 18 cases (5.1% of males), hepatic (2.5%), neurologic (1.7%), and heart (1.5%). Nine patients (1.7%) had more than 1 complication. In a multivariate analysis, diagnostic delay greater than 30 days (OR 2.0), ESR > 40 mm/hr (OR 1.9), and levels of alpha-2 globulin > 7.5 g/L (OR 6.8) were statistically significant independent variables associated with the presence of focal forms. Twenty-five patients with complications (14.8%) required surgical treatment. The relapse rate was 3.6% for those patients without complications and 4.1% for patients with focal forms (p > 0.05). However, when therapeutic failure, relapses, and mortality were considered together, the risk of an unfavorable evolution was significantly greater in patients with focal forms (10.6% versus 3.6% in patients without complications; OR 1.9, 95% CI 1.4-7.1, p < 0.005). Given the worse prognosis, knowledge and early diagnosis of the focal forms of B. melitensis infection is especially important.
              Article 0 comments Cited 94 times – based on 0 reviews     Review now
                Bookmark
                All references

                Author and article information

                Contributors
                Dania El Hallak:
                ORCID: https://orcid.org/0009-0001-7501-3063
                Mae Al Habbal:
                ORCID: https://orcid.org/0009-0000-4493-9499
                Journal
                Journal ID (nlm-ta): Case Rep Crit Care
                Journal ID (iso-abbrev): Case Rep Crit Care
                Journal ID (publisher-id): CRICC
                Title: Case Reports in Critical Care
                Publisher: Hindawi
                ISSN (Print): 2090-6420
                ISSN (Electronic): 2090-6439
                Publication date Collection: 2023
                Publication date (Electronic): 11 November 2023
                Volume: 2023
                Electronic Location Identifier: 5513052
                Affiliations
                1Beirut Arab University, Beirut, Lebanon
                2Lebanese University, Lebanon
                Author notes

                Academic Editor: Mehmet Doganay

                Author information
                https://orcid.org/0009-0001-7501-3063
                https://orcid.org/0009-0000-4493-9499
                https://orcid.org/0000-0002-4261-6474
                Article
                DOI: 10.1155/2023/5513052
                PMC ID: 10657239
                SO-VID: 76a7b611-d68e-47ea-9d2a-026b0923680b
                Copyright © Copyright © 2023 Dania El Hallak et al.
                License:

                This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                Date received : 12 July 2023
                Date revision received : 23 October 2023
                Date accepted : 3 November 2023
                Categories
                Subject: Case Report

                Data availability:

                Comments

                Comment on this article