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      Risk factors associated with surgical site infections following joint replacement surgery: a narrative review

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          Abstract

          Background

          Surgical site infection following joint replacement surgery is still a significant complication, resulting in repeated surgery, prolonged antibiotic therapy, extended postoperative hospital stay, periprosthetic joint infection, and increased morbidity and mortality. This review discusses the risk factors associated with surgical site infection.

          Related risk factors

          The patient-related factors include sex, age, body mass index (BMI), obesity, nutritional status, comorbidities, primary diagnosis, living habits, and scores of the American Society of Anesthesiologists physical status classification system, etc. Surgery-related factors involve preoperative skin preparation, prolonged duration of surgery, one-stage bilateral joint replacement surgery, blood loss, glove changes, anti-microbial prophylaxis, topical anti-bacterial preparations, wound management, postoperative hematoma, etc. Those risk factors are detailed in the review.

          Conclusion

          Preventive measures must be taken from multiple perspectives to reduce the incidence of surgical site infection after joint replacement surgery.

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          Most cited references79

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          Economic burden of periprosthetic joint infection in the United States.

          This study characterizes the patient and clinical factors influencing the economic burden of periprosthetic joint infection (PJI) in the United States. The 2001-2009 Nationwide Inpatient Sample was used to identify total hip and knee arthroplasties using International Classification of Diseases, Ninth Revision, procedure codes. The relative incidence of PJI ranged between 2.0% and 2.4% of total hip arthroplasties and total knee arthroplasties and increased over time. The mean cost to treat hip PJIs was $5965 greater than the mean cost for knee PJIs. The annual cost of infected revisions to US hospitals increased from $320 million to $566 million during the study period and was projected to exceed $1.62 billion by 2020. As the demand for joint arthroplasty is expected to increase substantially over the coming decade, so too will the economic burden of prosthetic infections. Copyright © 2012. Published by Elsevier Inc.
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            Periprosthetic joint infection.

            Periprosthetic joint infections are a devastating complication after arthroplasty and are associated with substantial patient morbidity. More than 25% of revisions are attributed to these infections, which are expected to increase. The increased prevalence of obesity, diabetes, and other comorbidities are some of the reasons for this increase. Recognition of the challenge of surgical site infections in general, and periprosthetic joint infections particularly, has prompted implementation of enhanced prevention measures preoperatively (glycaemic control, skin decontamination, decolonisation, etc), intraoperatively (ultraclean operative environment, blood conservation, etc), and postoperatively (refined anticoagulation, improved wound dressings, etc). Additionally, indications for surgical management have been refined. In this Review, we assess risk factors, preventive measures, diagnoses, clinical features, and treatment options for prosthetic joint infection. An international consensus meeting about such infections identified the best practices and further research needs. Orthopaedics could benefit from enhanced preventive, diagnostic, and treatment methods.
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              Clinical practice. Infection associated with prosthetic joints.

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                Author and article information

                Contributors
                cpk464@yahoo.com.hk
                Journal
                Arthroplasty
                Arthroplasty
                Arthroplasty
                BioMed Central (London )
                2524-7948
                1 May 2022
                1 May 2022
                2022
                : 4
                : 11
                Affiliations
                [1 ]GRID grid.412521.1, ISNI 0000 0004 1769 1119, Department of Joint Surgery, , The Affiliated Hospital of Qingdao University, ; Qingdao, China
                [2 ]GRID grid.194645.b, ISNI 0000000121742757, Department of Orthopaedics &, , Traumatology Queen Mary Hospital, The University of Hong Kong, ; 102 Pok Fu Lam Road, Hong Kong SAR, China
                Author information
                http://orcid.org/0000-0002-1969-0895
                Article
                113
                10.1186/s42836-022-00113-y
                9057059
                35490250
                78610c53-d457-4b3a-974d-3e7c9a3e8a4b
                © The Author(s) 2022

                Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

                History
                : 14 September 2021
                : 31 December 2021
                Categories
                Review
                Custom metadata
                © The Author(s) 2022

                surgical site infection,risk factor,joint replacement

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