Rieko Bessho: Role: Data curationRole: Formal analysisRole: InvestigationRole: MethodologyRole:
Writing – original draftRole: Writing – review & editing
Kazuhiro Kashiwagi:
ORCID: https://orcid.org/0000-0002-6301-1466
Role: ConceptualizationRole: Formal analysisRole: InvestigationRole: MethodologyRole:
Project administrationRole: SupervisionRole: Writing – review & editing
Akihiko Ikura: Role: Formal analysisRole: InvestigationRole: MethodologyRole: Writing – review &
editing
Karin Yamataka: Role: Formal analysisRole: Funding acquisitionRole: InvestigationRole: Writing – review
& editing
Jun Inaishi: Role: InvestigationRole: MethodologyRole: Writing – review & editing
Hiromasa Takaishi: Role: Project administrationRole: Writing – review & editing
Takanori Kanai: Role: ConceptualizationRole: Project administrationRole: Writing – review & editing
Christina Chan: Role: Editor
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS One
Journal ID (publisher-id): plos
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
31
May
2022
Publication date Collection: 2022
Volume: 17
Issue: 5
Electronic Location Identifier: e0269265
Affiliations
[1
]
Center for Preventive Medicine, Keio University Hospital, Tokyo, Japan
[2
]
Hills Future Preventive Medicine and Wellness, Keio University, Tokyo, Japan
[3
]
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio
University, Tokyo, Japan
Michigan State University, UNITED STATES
Author notes
Competing Interests: The authors have declared that no competing interests exist.
Author information
Article
Publisher ID:
PONE-D-21-39353
DOI: 10.1371/journal.pone.0269265
PMC ID: 9154100
PubMed ID: 35639744
SO-VID: 78ba5abd-ca29-4d4c-bda1-77c9e4e0e318
Copyright © © 2022 Bessho et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
KK belongs to the joint research course (Hills Future Preventive Medicine and Wellness,
Keio University, Tokyo, Japan) funded by Mori Building Co., Ltd (
https://www.mori.co.jp). The funder had no role in study design, data collection and analysis, decision
to publish, or preparation of the manuscript.
Subject:
Research Article
Subject:
Medicine and Health Sciences
Subject:
Vascular Medicine
Subject:
Atherosclerosis
Subject:
Medicine and Health Sciences
Subject:
Endocrinology
Subject:
Endocrine Disorders
Subject:
Diabetes Mellitus
Subject:
Medicine and Health Sciences
Subject:
Medical Conditions
Subject:
Metabolic Disorders
Subject:
Diabetes Mellitus
Subject:
Medicine and Health Sciences
Subject:
Gastroenterology and Hepatology
Subject:
Liver Diseases
Subject:
Fatty Liver
Subject:
Biology and Life Sciences
Subject:
Physiology
Subject:
Physiological Parameters
Subject:
Body Weight
Subject:
Obesity
Subject:
Medicine and Health Sciences
Subject:
Medical Conditions
Subject:
Cardiovascular Diseases
Subject:
Coronary Heart Disease
Subject:
Medicine and Health Sciences
Subject:
Cardiology
Subject:
Cardiovascular Medicine
Subject:
Cardiovascular Diseases
Subject:
Coronary Heart Disease
Subject:
Medicine and Health Sciences
Subject:
Vascular Medicine
Subject:
Coronary Heart Disease
Subject:
Biology and Life Sciences
Subject:
Physiology
Subject:
Physiological Processes
Subject:
Calcification
Subject:
Biology and Life Sciences
Subject:
Developmental Biology
Subject:
Fibrosis
Subject:
Medicine and Health Sciences
Subject:
Endocrinology
Subject:
Endocrine Physiology
Subject:
Insulin Resistance
Subject:
Biology and Life Sciences
Subject:
Physiology
Subject:
Endocrine Physiology
Subject:
Insulin Resistance