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      Advantage of Using 8K Ultra-High-Definition Television System for Kasai Portoenterostomy for Biliary Atresia

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          Abstract

          Kasai portoenterostomy (KPE) is currently the first-line treatment for biliary atresia. Many pediatric surgeons have reported that the dissection of the fibrous remnant at the porta hepatis is one of the most important components of this procedure. Furthermore, laparoscopic portoenterostomy is being increasingly used to treat biliary atresia.

          An advantage of laparoscopic surgery is that surgeons can more easily identify microbiliary ducts, owing to the magnification. We report the case of a 61-day-old girl on whom we performed an exploratory laparotomy and diagnosed type III biliary atresia using intraoperative cholangiography. For the first time, we performed an open KPE using an 8K ultra-high-definition television system. This allowed us to clearly view the porta hepatis and to successfully perform the portoenterostomy.

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          Most cited references11

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          Biliary atresia in England and Wales: results of centralization and new benchmark.

          Biliary atresia (BA) is a rare, potentially life-threatening condition of the newborn presenting with conjugated jaundice. Typically, it is treated by an initial attempt to restore bile flow (the Kasai portoenterostomy [KP]) as soon as possible after diagnosis and, if this fails, liver transplantation. Since 1999, the treatment of BA has been centralized to 3 centers in England and Wales able to offer both treatment options. The aim of this study was to review the outcome of this policy change and provide a national benchmark. The management of all infants born within England and Wales during the period January 1999 to December 2009 was assessed using 3 key performance indicators such as median time to KP, percentage clearance of jaundice (≤20 mol/L) post-KP, and 5- and 10-year native liver and true survival estimates. Data are quoted as median (range), and P < .05 was considered significant. A total of 443 infants had confirmed BA; and of these, most were isolated BA (n = 359), with 84 having other significant anomalies (but predominantly BA splenic malformation syndrome). Four infants died before any biliary intervention. Kasai portoenterostomy was performed in 424 infants (median age, 54 [range 7-209] days), and a primary liver transplant was performed in 15. Clearance of jaundice post-KP was achieved in 232 (55%). There were 41 deaths, including 4 (10%) without any intervention, 24 (58%) post-KP usually because of end-stage liver disease and mostly on a transplant waiting list, and 13 (32%) post-LT usually because of multiorgan failure. Overall, the 5- and 10-year native liver survival estimates were 46% (95% confidence interval [CI], 41-51) and 40% (95% CI, 34-46), respectively. The 5- and 10-year true patient survival estimates were 90% (95% CI, 88-93) and 89% (95% CI, 86-93), respectively. Outcome was worse for those with other anomalies (lower clearance of jaundice post-KP [43% vs 57%; odds ratio, 1.7; 95% CI, 1.04-2.8]; P = .02) and an increased mortality overall (eg, at 5 years, 72 [95% CI, 64-83] vs 94 [95% CI, 91-96]; χ(2) = 33; P < .0001). National outcome measures in BA appear better than those from previously published series from comparable countries and may be attributed to centralization of surgical and medical resources. Copyright © 2011 Elsevier Inc. All rights reserved.
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            Japanese Biliary Atresia Registry

            Masaki Nio (2017)
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              Prognosis of biliary atresia in the era of liver transplantation: French national study from 1986 to 1996.

              Since the sequential treatment of Kasai operation with or without liver transplantation became available, the overall prognosis of biliary atresia remains unclear. This study examined the prognostic factors from diagnosis. All patients with biliary atresia living in France and born in the years 1986 to 1996 were reviewed. Actuarial survival rates were calculated for survival with native liver, survival after liver transplantation, and overall survival. Potential prognostic factors were analyzed using the logrank test and the Cox model. A total of 472 patients were identified. Ten-year overall survival was 68%. Independent prognostic factors for overall survival were (S = 10-year rates) performance of Kasai operation (performed: S = 69%; not performed: S = 50%), age at Kasai operation ( 45 days: S = 66%), anatomical pattern of extrahepatic bile ducts, polysplenia syndrome, experience of the center ( /=20 [1 center]: S = 78%). Survival with native liver depended on the same independent prognostic factors. In conclusion (1) Kasai operation remains the first line treatment of BA, and (2) early performance of Kasai operation and treatment in an experienced center reduces the need for liver transplantation in infancy and childhood and provides children with the best chance of survival.
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                Author and article information

                Journal
                European J Pediatr Surg Rep
                European J Pediatr Surg Rep
                10.1055/s-00024358
                European Journal of Pediatric Surgery Reports
                Georg Thieme Verlag KG (Rüdigerstraße 14, 70469 Stuttgart, Germany )
                2194-7619
                2194-7627
                January 2021
                27 January 2021
                : 9
                : 1
                : e5-e8
                Affiliations
                [1 ]Division of Pediatric Surgery, Department of Surgery, Asahikawa Medical University, Asahikawa, Hokkaido, Japan
                [2 ]Division of Gastrointestinal Surgery, Department of Surgery, Asahikawa Medical University, Asahikawa, Hokkaido, Japan
                [3 ]Department of Vascular Surgery, Asahikawa Medical University, Asahikawa, Hokkaido, Japan
                Author notes
                Address for correspondence Hisayuki Miyagi, MD, PhD Division of Pediatric Surgery, Department of Surgery, Asahikawa Medical University Asahikawa, Hokkaido 078-8510Japan miyagi@ 123456mvj.biglobe.ne.jp
                Author information
                http://orcid.org/0000-0001-6504-2197
                Article
                200553cr
                10.1055/s-0040-1721466
                7840226
                33532171
                7ca83be7-bc61-4519-b29d-610ee5378eae
                The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. ( https://creativecommons.org/licenses/by/4.0/ )

                This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 30 July 2020
                : 09 October 2020
                Funding
                Funding None.
                Categories
                Case Report

                biliary atresia,8k ultra-high-definition television system,kasai portoenterostomy,kasai procedure

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