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      Four erroneous beliefs thwarting more trustworthy research

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          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          A range of problems currently undermines public trust in biomedical research. We discuss four erroneous beliefs that may prevent the biomedical research community from recognizing the need to focus on deserving this trust, and thus which act as powerful barriers to necessary improvements in the research process.

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          Reproducible research in computational science.

          Roger Peng (2011)
          Computational science has led to exciting new developments, but the nature of the work has exposed limitations in our ability to evaluate published findings. Reproducibility has the potential to serve as a minimum standard for judging scientific claims when full independent replication of a study is not possible.
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            Rescuing US biomedical research from its systemic flaws.

            B. Alberts, M Kirschner, S. Tilghman … (2014)
            The long-held but erroneous assumption of never-ending rapid growth in biomedical science has created an unsustainable hypercompetitive system that is discouraging even the most outstanding prospective students from entering our profession--and making it difficult for seasoned investigators to produce their best work. This is a recipe for long-term decline, and the problems cannot be solved with simplistic approaches. Instead, it is time to confront the dangers at hand and rethink some fundamental features of the US biomedical research ecosystem.
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              Scientists behaving badly.

              Brian Martinson, Melissa Anderson, Raymond de Vries (2005)
              Article 0 comments Cited 267 times – based on 0 reviews     Review now
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                Author and article information

                Contributors
                Mark Yarborough:
                ORCID: https://orcid.org/0000-0001-8188-4968
                Peter Rodgers: Role: Senior Editor
                Emma Pewsey: Role: Reviewing Editor
                Journal
                Journal ID (nlm-ta): eLife
                Journal ID (iso-abbrev): Elife
                Journal ID (publisher-id): eLife
                Title: eLife
                Publisher: eLife Sciences Publications, Ltd
                ISSN (Electronic): 2050-084X
                Publication date (Electronic, pub): 29 July 2019
                Publication date Collection: 2019
                Volume: 8
                Electronic Location Identifier: e45261
                Affiliations
                [1 ]deptBioethics Program University of California, Davis SacramentoUnited States
                [2 ]deptDepartment of Human Genetics McGill University MontrealCanada
                [3 ]Independent researcher MarseilleFrance
                eLife United Kingdom
                eLife United Kingdom
                eLife United Kingdom
                The University of Edinburgh United Kingdom
                Federal University of Rio de Janeiro Brazil
                Author information
                https://orcid.org/0000-0001-8188-4968
                Article
                Publisher ID: 45261
                DOI: 10.7554/eLife.45261
                PMC ID: 6688856
                PubMed ID: 31355746
                SO-VID: 7dee23e4-3bf0-49c0-b2f4-9547222c9c21
                Copyright © © 2019, Yarborough et al
                License:

                This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.

                History
                Date received : 17 January 2019
                Date accepted : 25 July 2019
                Funding
                The authors declare that there was no funding for this work
                Categories
                Subject: Feature Article
                Subject: Point of View
                Custom metadata
                Author impact statement Strategies to improve public trust in biomedical research are being hindered by a scientific mindset that stifles interest in reform.

                ScienceOpen disciplines: Life sciences
                Keywords: trustworthy research,quality improvement,research reforms,reproducibility,point of view,none
                Data availability:
                ScienceOpen disciplines: Life sciences
                Keywords: trustworthy research, quality improvement, research reforms, reproducibility, point of view, none

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