Factors that influence follicle recruitment, growth and ovulation during ovarian superstimulation in heifers: Opportunities to increase ovulation rate and embryo recovery by delaying the exposure of follicles to LH
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Abstract
The outcome of ovarian follicular superstimulation protocols in heifers is influenced
by the number of follicles that are stimulated to grow and the number induced to ovulate.
At present, only a proportion of the follicles that are stimulated to grow progress
to ovulation. The argument is developed in this review that failure of some of these
follicles to ovulate may be due not to an intrinsic deficiency but rather to their
relatively small size when the FSH treatment is initiated. Consequently, these follicles
do not have the opportunity to undergo full maturation within the time frame of a
conventional superstimulation protocol Based on this argument, we propose that delaying
the LH surge would allow for completion of maturation by a greater number of follicles,
resulting in an increased ovulation rate and in recovery of a greater number of viable
embryos.