Effects of nefopam on early postoperative hyperalgesia after cardiac surgery.

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Abstract

The purpose of this randomized, double-blind placebo-controlled study was to evaluate the effect of nefopam, a centrally acting antinociceptive compound, on the development of hyperalgesia after sternotomy. Preventive strategy giving nefopam from the early stage of anesthesia was compared with a postoperative strategy only and placebo.

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Journal

Journal ID (iso-abbrev): J. Cardiothorac. Vasc. Anesth.

Title: Journal of cardiothoracic and vascular anesthesia

Publisher: Elsevier BV

ISSN (Electronic): 1532-8422

ISSN (Print): 1053-0770

Publication date (Electronic): Jun 2013

Volume: 27

Issue: 3

Affiliations

[1 ] Department of Anesthesiology and Pain Medicine, University of Washington Medical Center, Seattle, WA 98195-6540, USA. prichebe@u.washington.edu

Article

Publisher Item ID: S1053-0770(12)00428-4

DOI: 10.1053/j.jvca.2012.08.015

PubMed ID: 23063945

SO-VID: 81da5ba6-6b5b-421d-b244-237fe2d1656f

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