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      Application of Hydroxytyrosol in the Functional Foods Field: From Ingredient to Dietary Supplements

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          Abstract

          Hydroxytyrosol (HT) is an amphipathic functional phenol found in the olive tree, both in its leaves and fruits, in free or bound forms, as well as in olive oil and by-products of olive oil manufacture. The European Food Safety Authority recommends regular consumption of HT due to its several beneficial effects on human health, which are closely associated to its antioxidant activity. These reasons make HT an excellent candidate for application as a functional ingredient in the design of novel food products. Patents already exist for methodologies of extraction, purification, and application of HT in supplements and food products. The present review discusses the impact of HT incorporation on food properties and its effects on consumers, based on relevant data related to the use of HT as a functional ingredient, both as a pure compound or in the form of HT-rich extracts, in various food products, namely in edible oils, beverages, bakery products, as well animal-based foods such as meat, fishery and dairy products.

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          Most cited references120

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          Free radical-scavenging properties of olive oil polyphenols.

          Plants in the Mediterranean basin, such as vine and olive trees, have developed an array of antioxidant defences to protect themselves from environmental stress. Accordingly, the incidence of coronary heart disease and certain cancers is lower in the Mediterranean area, where olive oil is the dietary fat of choice. As opposed to other vegetable oils, extra virgin olive oil, which is obtained by physical pressure from a whole fruit, is rich in phenolic components that are responsible for the particular stability of the oil. We have investigated the scavenging actions of some olive oil phenolics, namely hydroxytyrosol and oleuropein, with respect to superoxide anion generation, neutrophils respiratory burst, and hypochlorous acid. The low EC50S indicate that both compounds are potent scavengers of superoxide radicals and inhibitors of neutrophils respiratory burst: whenever demonstrated in vivo, these properties may partially explain the observed lower incidence of CHD and cancer associated with the Mediterranean diet.
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            Essential oils as natural additives to prevent oxidation reactions in meat and meat products: A review

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              Bioactive compounds in wine: Resveratrol, hydroxytyrosol and melatonin: A review

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                Author and article information

                Journal
                Antioxidants (Basel)
                Antioxidants (Basel)
                antioxidants
                Antioxidants
                MDPI
                2076-3921
                08 December 2020
                December 2020
                : 9
                : 12
                : 1246
                Affiliations
                LAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal; afrs@ 123456ua.pt (A.F.R.S.); danielaresende@ 123456outlook.com (D.R.); marianaicnamonteiro@ 123456gmail.com (M.M.); mac@ 123456ua.pt (M.A.C.); artur.silva@ 123456ua.pt (A.M.S.S.)
                Author notes
                [* ]Correspondence: susanacardoso@ 123456ua.pt ; Tel.: +351-234-370-360; Fax: +351-234-370-084
                Author information
                https://orcid.org/0000-0002-3148-8710
                https://orcid.org/0000-0002-1532-1152
                https://orcid.org/0000-0001-8898-6342
                https://orcid.org/0000-0003-2861-8286
                https://orcid.org/0000-0002-7882-737X
                Article
                antioxidants-09-01246
                10.3390/antiox9121246
                7763879
                33302474
                83df682e-5091-4955-8b6b-5a480f070eff
                © 2020 by the authors.

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).

                History
                : 14 November 2020
                : 03 December 2020
                Categories
                Review

                phenol,olive oil,by-products,table olives,antioxidant,functional ingredient,novel foods

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