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Effect of oral milrinone on mortality in severe chronic heart failure. The PROMISE Study Research Group.
M Packer
1 ,
J R Carver ,
R J Rodeheffer ,
R J Ivanhoe ,
R DiBianco ,
S M Zeldis ,
G H Hendrix ,
W J Bommer ,
U Elkayam ,
M L Kukin
Nov 21 1991
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Abstract
Milrinone, a phosphodiesterase inhibitor, enhances cardiac contractility by increasing intracellular levels of cyclic AMP, but the long-term effect of this type of positive inotropic agent on the survival of patients with chronic heart failure has not been determined.