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Effect of preoperative chemotherapy on local-regional disease in women with operable breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-18.
B Fisher
1 ,
A Brown ,
E Mamounas ,
S Wieand ,
A Robidoux ,
R G Margolese ,
A B Cruz ,
E R Fisher ,
D L Wickerham ,
N Wolmark ,
A DeCillis ,
J L Hoehn ,
A W Lees ,
N V Dimitrov
Jul 1997
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Abstract
To determine whether preoperative doxorubicin and cyclophosphamide (AC) permits more lumpectomies to be performed and decreases the incidence of positive nodes in women with primary breast cancer.