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      The Preparation and Structure Analysis Methods of Natural Polysaccharides of Plants and Fungi: A Review of Recent Development

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          Abstract

          Polysaccharides are ubiquitous biomolecules found in nature that contain various biological and pharmacological activities that are employed in functional foods and therapeutic agents. Natural polysaccharides are obtained mainly by extraction and purification, which may serve as reliable procedures to enhance the quality and the yield of polysaccharide products. Moreover, structural analysis of polysaccharides proves to be promising and crucial for elucidating structure–activity relationships. Therefore, this report summarizes the recent developments and applications in extraction, separation, purification, and structural analysis of polysaccharides of plants and fungi.

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          Biological activities and pharmaceutical applications of polysaccharide from natural resources: A review.

          Mingyue Shen, Yue Yu, Qianqian Song … (2018)
          Pharmacotherapy using natural substances can be currently regarded as a very promising future alternative to conventional therapy. As biological macromolecules, polysaccharide together with protein and polynucleotide, are extremely important biomacromoleules which play important roles in the growth and development of living organism. Polysaccharide is important component of higher plants, membrane of the animal cell and the cell wall of microbes. It is also closely related to the physiological functions. Recently, increasing attention has been paid on polysaccharides as an important class of bioactive natural products. Numerous researches have demonstrated the bioactivities of natural polysaccharides, which lead to the application of polysaccharides in the treatment of disease. In this paper, the various aspects of the investigation results of the bioactivities of polysaccharides were summarized, including its diversity pharmacological applications, such as immunoregulatory, anti-tumor, anti-virus, antioxidation, and hypoglycemic activity, and their application of polysaccharides in the treatment of disease are also discussed. We hope this review can offer some theoretical basis and inspiration for the mechanism study of the bioactivity of polysaccharides.
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            Raman and infrared spectroscopy of carbohydrates: A review

            Ewelina Wiercigroch, Ewelina Szafraniec, Krzysztof Czamara … (2017)
            Article 0 comments Cited 179 times – based on 0 reviews     Review now
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              Anticancer polysaccharides from natural resources: a review of recent research.

              Aizhen Zong, Hongzhi Cao, Fengshan Wang (2012)
              Taking into account the rising trend of the incidence of cancers of various organs, effective therapies are urgently needed to control human malignancies. However, almost all of the chemotherapy drugs currently on the market cause serious side effects. Fortunately, several previous studies have shown that some non-toxic biological macromolecules, including polysaccharides and polysaccharide-protein complexes, possess anti-cancer activities or can increase the efficacy of conventional chemotherapy drugs. Based on these encouraging observations, a great deal of effort has been focused on discovering anti-cancer polysaccharides and complexes for the development of effective therapeutics for various human cancers. This review focuses on the advancements in the anti-cancer efficacy of various natural polysaccharides and polysaccharide complexes in the past 5 years. Most polysaccharides were tested using model systems, while several involved clinical trials. Copyright © 2012 Elsevier Ltd. All rights reserved.
              Article 0 comments Cited 177 times – based on 0 reviews     Review now
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                Author and article information

                Journal
                Journal ID (nlm-ta): Molecules
                Journal ID (iso-abbrev): Molecules
                Journal ID (publisher-id): molecules
                Title: Molecules
                Publisher: MDPI
                ISSN (Electronic): 1420-3049
                Publication date (Electronic): 28 August 2019
                Publication date Collection: September 2019
                Volume: 24
                Issue: 17
                Electronic Location Identifier: 3122
                Affiliations
                [1 ]College of Pharmacy, Southwest Minzu University, Chengdu 610225, China
                [2 ]Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China
                [3 ]Department of Chemical and Biomolecular Engineering, University of California Berkeley, Berkeley, CA 94720, USA
                Author notes
                [* ]Correspondence: renyancd1985@ 123456163.com (Y.R.); zhang_zd@ 123456tib.cas.cn (Z.Z.); Tel.: +86-1819-073-3696 (Y.R.); +86-1366-217-0549 (Z.Z.)
                Author information
                https://orcid.org/0000-0001-5893-3557
                Article
                Publisher ID: molecules-24-03122
                DOI: 10.3390/molecules24173122
                PMC ID: 6749352
                PubMed ID: 31466265
                SO-VID: 8635d255-ce25-4f26-8b45-653343c5d74b
                Copyright © © 2019 by the authors.
                License:

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).

                History
                Date received : 25 July 2019
                Date accepted : 27 August 2019
                Categories
                Subject: Review

                Keywords: natural polysaccharides,plants and fungi,extraction,isolation,purification,structure analysis
                Data availability:
                Keywords: natural polysaccharides, plants and fungi, extraction, isolation, purification, structure analysis

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