Manda V. Sasidhar: Role: ConceptualizationRole: Data curationRole: Formal analysisRole: InvestigationRole:
MethodologyRole: ValidationRole: Writing – original draftRole: Writing – review &
editing
Sai Krishnaveni Chevooru: Role: InvestigationRole: Writing – review & editing
Oliver Eickelberg: Role: SupervisionRole: Writing – review & editing
Hans-Peter Hartung: Role: Funding acquisitionRole: SupervisionRole: Writing – review & editing
Oliver Neuhaus:
ORCID: http://orcid.org/0000-0002-5496-2243
Role: ConceptualizationRole: Data curationRole: Formal analysisRole: Funding acquisitionRole:
InvestigationRole: MethodologyRole: Project administrationRole: ResourcesRole: SupervisionRole:
ValidationRole: VisualizationRole: Writing – original draftRole: Writing – review
& editing
Martin Sebastian Weber: Role: Editor
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
18
December
2017
Publication date Collection: 2017
Volume: 12
Issue: 12
Electronic Location Identifier: e0189701
Affiliations
[1
]
Department of Neurology, Heinrich Heine University, Düsseldorf, Germany
[2
]
Apollo Hospitals Educational and Research Foundation, Hyderabad, India
[3
]
Department of Internal Medicine II, Molecular Biology and Medicine of the Lung, Justus
Liebig University, Giessen, Germany
[4
]
Wockhardt Research Centre, Aurangabad, India
[5
]
Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine,
University of Colorado, Aurora, CO, United States of America
[6
]
Department of Neurology, SRH Kliniken Landkreis Sigmaringen, Sigmaringen, Germany
Klinikum rechts der Isar der Technischen Universitat Munchen, GERMANY
Author notes
Competing Interests: The authors have declared that no competing interests exist.
Author information
Article
Publisher ID:
PONE-D-17-31988
DOI: 10.1371/journal.pone.0189701
PMC ID: 5734787
PubMed ID: 29253870
SO-VID: 86492133-aba4-499e-b263-6a8129cdb2af
License:
This is an open access article, free of all copyright, and may be freely reproduced,
distributed, transmitted, modified, built upon, or otherwise used by anyone for any
lawful purpose. The work is made available under the
Creative Commons CC0 public domain dedication.
Funded by: funder-id http://dx.doi.org/10.13039/501100001659, Deutsche Forschungsgemeinschaft;
Award Recipient
:
Manda V. Sasidhar
Funded by: funder-id http://dx.doi.org/10.13039/100009091, Justus Liebig Universität Gießen;
Award Recipient
:
Sai Krishnaveni Chevooru
This work was supported in part by grants from the Graduate College of the German
Research Foundation, “Pathological processes of the nervous system: from gene to behaviour”
(to MVS), and from the International Graduate Program of the Justus Liebig University
of Giessen, “Molecular Biology and Medicine of the Lung” (to SKC).
Subject:
Research Article
Subject:
Medicine and Health Sciences
Subject:
Pharmacology
Subject:
Drugs
Subject:
Statins
Subject:
Biology and Life Sciences
Subject:
Developmental Biology
Subject:
Cell Differentiation
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Lipids
Subject:
Cholesterol
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Blood Cells
Subject:
White Blood Cells
Subject:
Macrophages
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Macrophages
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Macrophages
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Macrophages
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Glycobiology
Subject:
Glycosylation
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Proteins
Subject:
Post-Translational Modification
Subject:
Glycosylation
Subject:
Medicine and Health Sciences
Subject:
Clinical Medicine
Subject:
Clinical Immunology
Subject:
Autoimmune Diseases
Subject:
Multiple Sclerosis
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Clinical Immunology
Subject:
Autoimmune Diseases
Subject:
Multiple Sclerosis
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Clinical Immunology
Subject:
Autoimmune Diseases
Subject:
Multiple Sclerosis
Subject:
Medicine and Health Sciences
Subject:
Neurology
Subject:
Demyelinating Disorders
Subject:
Multiple Sclerosis
Subject:
Medicine and Health Sciences
Subject:
Neurology
Subject:
Neurodegenerative Diseases
Subject:
Multiple Sclerosis
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Blood Cells
Subject:
White Blood Cells
Subject:
Monocytes
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Monocytes
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Monocytes
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Monocytes
Subject:
Research and Analysis Methods
Subject:
Spectrum Analysis Techniques
Subject:
Spectrophotometry
Subject:
Cytophotometry
Subject:
Flow Cytometry